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Patient P-02033

Synthetic patientMETA-24 · Day 172 · 35–44 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S06
  2. Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 GI-04 recommended — GI Support Protocol GI-04
  4. Day 23 Patient accepted — Started GI-04 in the companion
  5. Day 31 GI symptom burden −30% vs expected — GI Support Protocol GI-04
  6. Day 37 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days
  • Toxicity-11
  • Nutritional resilience-8
  • GI instability+5
  • Inflammatory activity-2

What helped?

  • GI Support Protocol GI-04Day 22
    Result: symptom burden −30%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
14 min
worsening · -2.4 vs previous 14 d
Sleep duration
Wearable
7.9 h
stable · +0.1 vs previous 14 d
Energy level
Daily log
6.5/10
improving · +0.4 vs previous 14 d
Steps
Wearable
2,250
worsening · -419 vs previous 14 d
GI burden
Companion
22.2/100
worsening · +1.3 vs previous 14 d
Adherence
Companion
96.8 %
stable · -1.5 vs previous 14 d
Sleep quality
Wearable
52/100
stable · -0.8 vs previous 14 d
Glucose, CGM daily mean
CGM
133 mg/dL
stable · -1.3 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 69 from the failing basin, 27 from restoration.

Good elements to keep
  • GI Support Protocol GI-04
    intervention · steering +21.1
  • Protein (supports)
    perturbation · steering +6.1
  • Protein
    supporter · GI -3.6 next day
Main detractors to watch
  • Low butyrate capacity
    hidden · steering -17.5
  • Poor metabolizer
    hidden · steering -12.7
  • Low microbial diversity
    hidden · steering -7.7
  • Caffeine
    perturbation · steering -5.9
  • Caffeine
    detractor · GI +3.3 next day
  • Ultra-processed food
    detractor · GI +2.9 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -3.6supporter · 95%
  • Caffeine
    +3.3detractor · 95%
  • Ultra-processed food
    +2.9detractor · 95%
  • Dietary fat load
    +2.8detractor · 95%
  • Alcohol
    +2.4detractor · 90%
  • Simple carbohydrates
    +2.3detractor · 74%
  • Histamine load
    -0.4no signal · 15%
  • Insoluble fibre
    +0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 38/100
  • Mucosal barrier integrity ↓30
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Autonomic recovery ↓20
    • Wearable2,250 steps/day
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 2.5 · butyrate capacity 38/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
37 ms
Sleep
7.8 h
Steps
2,740
Resting HR
74 bpm
Daily log: GI score 22, nutritional resilience 61, adherence 97.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0264557%S02HY-01improved56
P-0235156%S16——51
P-0221955%S13——60
P-0251354%S16GI-04no change46
P-0263954%S08——58
P-0223553%S14DT-01improved50
P-0203752%S04GI-04improved53
P-0215052%S11HY-01improved45
P-0220052%S13——47
P-0257352%S10——52
P-0207051%S11——55
P-0216951%S17——43