Patient P-02034
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
58%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S18
- Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 13.
Primary contributors, last 14 days
- Inflammatory activity-12
- GI instability-10
- Toxicity+5
- Nutritional resilience+4
- Treatment adherence+3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
65%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 86% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable4 min
worsening · -1.0 vs previous 14 d
Sleep duration
Wearable6.3 h
stable · +0.1 vs previous 14 d
Energy level
Daily log2.8/10
improving · +0.4 vs previous 14 d
Steps
Wearable300
stable · -22 vs previous 14 d
GI burden
Companion60.1/100
stable · -1.6 vs previous 14 d
Adherence
Companion67.2 %
worsening · -4.9 vs previous 14 d
Sleep quality
Wearable18.8/100
improving · +0.7 vs previous 14 d
Glucose, CGM daily mean
CGM145 mg/dL
stable · -1.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 40 from the failing basin, 57 from restoration.
Would help
- GI-04 GI Support Protocol74% improved among 66 similar · onset 8 d · confidence 62%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 66%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 66%
- More proteinGI -6.1 next day on high-intake days · n 20
Would not help
- Keep ultra-processed lowGI +5.9 next day on high-intake days · n 18
- Keep simple carbs lowGI +5 next day on high-intake days · n 19
- Keep histamine lowGI +3.9 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.1supporter · 95%
- Ultra-processed food+5.9detractor · 95%
- Simple carbohydrates+5detractor · 95%
- Histamine load+3.9detractor · 95%
- Alcohol-1.9no signal · 41%
- Insoluble fibre-1.5no signal · 25%
- Caffeine+0.8no signal · 18%
- Dietary fat load-0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 60 and rising
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 57
- WearableHRV 15 ms, trending down
- Autonomic recovery ↑65
- WearableResting HR 82 bpm
- Wearable300 steps/day
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 57
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.1 · butyrate capacity 47/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 17 ms
- Sleep
- 6.1 h
- Steps
- 651
- Resting HR
- 83 bpm
Daily log: GI score 60, nutritional resilience 36, adherence 67.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.