Patient P-02060
Synthetic patientMETA-24 · Day 108 · 25–34 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
58%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 47 NP-02 recommended — Dietary Support Protocol NP-02
- Day 48 Patient accepted — Started NP-02 in the companion
- Day 58 GI symptom burden −16% vs expected — Dietary Support Protocol NP-02
- Day 64 Tolerance state changed — Unstable → Improving
- Day 69 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 72 GI-04 recommended — GI Support Protocol GI-04
- Day 73 Patient accepted — Started GI-04 in the companion
- Day 81 GI symptom burden −19% vs expected — GI Support Protocol GI-04
- Day 87 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 69.
Primary contributors, last 14 days
- Treatment adherence-16
- GI instability-7
- Toxicity+7
- Nutritional resilience-4
- Inflammatory activity-3
What helped?
- Dietary Support Protocol NP-02Day 47Result: symptom burden −16%
- GI Support Protocol GI-04Day 72Result: symptom burden −19%
LIFE OS recommendation
Supportive Compound SC-12
60%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 75% showed improvement
- median effect visible after 6 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable49 min
worsening · -6.4 vs previous 14 d
Sleep duration
Wearable6.4 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log3.1/10
worsening · -1.4 vs previous 14 d
Steps
Wearable6,182
worsening · -708 vs previous 14 d
GI burden
Companion48.2/100
worsening · +13.4 vs previous 14 d
Adherence
Companion68 %
worsening · -14.9 vs previous 14 d
Sleep quality
Wearable31.5/100
worsening · -8.0 vs previous 14 d
Glucose, CGM daily mean
CGM145 mg/dL
stable · +2.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 41 from the failing basin, 47 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 34 similar · onset 3 d · confidence 64%
- SC-12 Supportive Compound72% improved among 25 similar · onset 6 d · confidence 64%
- CR-01 Clinician Review100% improved among 6 similar · onset 5 d · confidence 64%
- More proteinGI -6.7 next day on high-intake days · n 19
Would not help
- Keep fat lowGI +6.5 next day on high-intake days · n 19
- Keep simple carbs lowGI +5.1 next day on high-intake days · n 19
- Keep ultra-processed lowGI +4.5 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.7supporter · 95%
- Dietary fat load+6.5detractor · 95%
- Simple carbohydrates+5.1detractor · 95%
- Ultra-processed food+4.5detractor · 78%
- Insoluble fibre+4.1detractor · 56%
- Alcohol+3.3detractor · 74%
- Caffeine+1no signal · 17%
- Histamine load-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 37/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 48 and rising
- Autonomic recovery ↓45
- WearableResting HR 72 bpm
- WearableShort sleep window
- Inflammatory signalling ↓25
- BloodInflammatory load index 49
- Drug metabolism and exposure ↑20
- BloodToxicity index 47
DNA
Fictional pharmacogenomic panel
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.7 · butyrate capacity 37/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 42 ms
- Sleep
- 5.8 h
- Steps
- 5,903
- Resting HR
- 75 bpm
Daily log: GI score 48, nutritional resilience 39, adherence 68.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.