Patient P-02115
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
76%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 67 SC-12 recommended — Supportive Compound SC-12
- Day 68 Patient accepted — Started SC-12 in the companion
- Day 71 GI-04 recommended — GI Support Protocol GI-04
- Day 72 Patient accepted — Started GI-04 in the companion
- Day 74 GI symptom burden −21% vs expected — Supportive Compound SC-12
- Day 80 GI symptom burden −33% vs expected — GI Support Protocol GI-04
- Day 80 Tolerance state changed — Unstable → Improving
- Day 86 Tolerance state changed — Unstable → Improving
- Day 88 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 88.
Primary contributors, last 14 days
- GI instability+24
- Nutritional resilience-20
- Inflammatory activity+17
- Toxicity+11
- Treatment adherence-5
What helped?
- Supportive Compound SC-12Day 67Result: symptom burden −21%
- GI Support Protocol GI-04Day 71Result: symptom burden −33%
LIFE OS recommendation
Hydration Protocol HY-01
61%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 63% showed improvement
- median effect visible after 4 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 27/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 47 and rising
- Autonomic recovery ↓45
- WearableResting HR 78 bpm
- Wearable2,466 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 40
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.4 · butyrate capacity 27/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 7.0 h
- Steps
- 3,015
- Resting HR
- 75 bpm
Daily log: GI score 47, nutritional resilience 44, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02298 | 49% | S14 | GI-04 | improved | 65 |
| P-02102 | 43% | S14 | GI-04 | improved | 64 |
| P-02575 | 42% | S14 | ME-01 | improved | 73 |
| P-02252 | 36% | S02 | — | — | 65 |
| P-02309 | 36% | S09 | — | — | 67 |
| P-02060 | 35% | S14 | GI-04 | improved | 54 |
| P-02659 | 34% | S09 | — | — | 69 |
| P-02299 | 33% | S14 | GI-04 | improved | 59 |
| P-02379 | 33% | S15 | — | — | 63 |
| P-02388 | 33% | S11 | — | — | 75 |
| P-02587 | 33% | S14 | — | — | 64 |
| P-02689 | 33% | S13 | — | — | 91 |