Patient P-02078
Synthetic patientMETA-24 · Day 154 · 45–54 · F · baseline S04Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Stable
Inflammatory state
Stable
Nutritional resilience
Stable
Discontinuation risk
53%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S04
- Day 23 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 23.
Primary contributors, last 14 days
- Treatment adherence-7
- Inflammatory activity-3
- Toxicity-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
64%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 89% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable18 min
worsening · -4.6 vs previous 14 d
Sleep duration
Wearable5.4 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log2.8/10
worsening · -0.9 vs previous 14 d
Steps
Wearable1,981
worsening · -532 vs previous 14 d
GI burden
Companion56.7/100
worsening · +11.8 vs previous 14 d
Adherence
Companion68.6 %
worsening · -11.2 vs previous 14 d
Sleep quality
Wearable25.3/100
worsening · -7.3 vs previous 14 d
Glucose, CGM daily mean
CGM139 mg/dL
stable · +2.3 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 37 from the failing basin, 54 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +9.1
- Butyrate producers intacthidden · steering +7.5
- Daily walks resumedperturbation · steering +3.3
- Proteinsupporter · GI -5 next day
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- Ultra-processed foodperturbation · steering -8
- Low microbial diversityhidden · steering -7.7
- Bacteroides fragilis elevatedhidden · steering -7.4
- Ultra-processed fooddetractor · GI +4.5 next day
- Simple carbohydratesdetractor · GI +4.1 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5supporter · 95%
- Ultra-processed food+4.5detractor · 95%
- Simple carbohydrates+4.1detractor · 95%
- Caffeine+2.9detractor · 81%
- Alcohol+2.7detractor · 73%
- Histamine load-1.6no signal · 39%
- Insoluble fibre-1no signal · 19%
- Dietary fat load-0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 53
- Autonomic recovery ↑65
- WearableResting HR 75 bpm
- Wearable1,981 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 48
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 57 and rising
- WearableSleep 5.4 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.9 · butyrate capacity 46/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 35 ms
- Sleep
- 5.4 h
- Steps
- 2,936
- Resting HR
- 78 bpm
Daily log: GI score 57, nutritional resilience 43, adherence 69.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02009 | 43% | S08 | CR-01 | improved | 64 |
| P-02160 | 43% | S03 | — | — | 45 |
| P-02233 | 43% | S16 | CR-01 | improved | 66 |
| P-02321 | 43% | S17 | GI-04 | improved | 54 |
| P-02595 | 43% | S02 | — | — | 53 |
| P-02054 | 42% | S01 | CR-01 | improved | 57 |
| P-02252 | 42% | S02 | — | — | 65 |
| P-02433 | 42% | S07 | GI-04 | improved | 61 |
| P-02309 | 41% | S09 | — | — | 67 |
| P-02334 | 41% | S04 | GI-04 | improved | 66 |
| P-02530 | 41% | S07 | — | — | 67 |
| P-02084 | 40% | S11 | GI-04 | no change | 58 |