DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
55/100
vs baseline (day 0)
+1
1 improved · 3 worsened
synthetic signature · consistent with this patient's biology
- 1 opportunist above range: Enterococcus faecium
- 4 keystone species absent
- Shannon 2.44 (expected ≥ 3)
- 7 resistance genes
- Tissue recycling index 51
Pathogens / opportunists1/5
↓ from 2
Keystone species4/8
Diversity1/2
Metabolic modules0/4
Vitamin synthesis4/7
↑ from 3
Oral translocation1/1
Host DNA0/1
Tissue recycling1/1
Central mechanisms1/2
↑ from 0
Virulence factors4/4
Antibiotic resistance genes7/7
↑ from 6
Genetic predisposition1/1
Opportunists above range
Enterococcus faecium 11.684% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum, Butyricicoccus pullicaecorum, Eubacterium rectale
Capacity
Shannon 2.44 · butyrate 520 CPM · SCFA 832
4 vitamins below
Host & mechanisms
tissue recycling 51/100
oral translocation 5.31% AR
molecular_mimicry above
7 resistance genes · 4 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.217 % AR · in range | 0.19 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.005 % AR · in range | 0.154 % AR · in range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 9.946 % AR · above range | 11.684 % AR · above range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.063 % AR · in range | 0.006 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 1.989 % AR · above range | 0 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.03 % AR · in range | 0.98 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.88 % AR · in range | 0.82 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 1.16 % AR · in range | 0.21 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.68 % AR · in range | 1.47 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.5 · below range | 2.44 · below range | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 103 specii · in range | 100 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 536 CPM · in range | 520 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 985 CPM · in range | 832 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 293 CPM · in range | 254 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 109 CPM · in range | 102 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 329 CPM · below range | 417 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 296 CPM · below range | 385 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 172 CPM · below range | 422 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3595 CPM · in range | 488 CPM · below range(worsened) | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 2709 CPM · in range | 3591 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3057 CPM · in range | 3855 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 4480 CPM · in range | 3925 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 4.53 % AR · above range | 5.31 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 161 pb · in range | 156 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 42 /100 · above range | 51 /100 · above range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 61 /100 · in range | 68 /100 · above range(worsened) | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 59 /100 · in range | 61 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 4
| fimD outer membrane usher | 91 potriviri/M · present | 34 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 89 potriviri/M · present | 71 potriviri/M · present | expected absent | Virulence factor detected. |
| irp2 yersiniabactin synthetase | 57 potriviri/M · present | 33 potriviri/M · present | expected absent | Virulence factor detected. |
| espX4 type III secretion | 35 potriviri/M · present | 45 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 7
| sul1 | 5 citiri/M · present | 5.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 7.3 citiri/M · present | 9.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 1.2 citiri/M · present | 8.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 10.6 citiri/M · present | 7.9 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 5.2 citiri/M · present | 3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| dfrA1 | 6.8 citiri/M · present | 5.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| APH(6)-Id | — | 9.3 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 1
| CYP2D6 | 3.37 OR · risk variant | 1.8 OR · risk variant | expected reference genotype | Expected exposure |