DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
38/100
vs baseline (day 0)
-9
3 improved · 2 worsened
synthetic signature · consistent with this patient's biology
- 2 opportunists above range: Escherichia coli, Enterococcus faecium
- 2 keystone species absent
- 5 resistance genes
- Host DNA fragmentation atypical
Pathogens / opportunists2/5
↓ from 3
Keystone species2/8
Diversity0/2
↓ from 1
Metabolic modules0/4
Vitamin synthesis2/7
Oral translocation1/1
Host DNA1/1
↑ from 0
Tissue recycling0/1
↓ from 1
Central mechanisms0/2
Virulence factors2/2
Antibiotic resistance genes5/5
↑ from 4
Genetic predisposition2/2
Opportunists above range
Escherichia coli 10.979% AR
Enterococcus faecium 5.49% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 3.07 · butyrate 738 CPM · SCFA 1204
2 vitamins below
Host & mechanisms
host DNA fragmentation atypical
tissue recycling 34/100
oral translocation 2.52% AR
5 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 12.831 % AR · above range | 10.979 % AR · above range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.224 % AR · in range | 0.164 % AR · in range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 6.415 % AR · above range | 5.49 % AR · above range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.074 % AR · in range | 0.001 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 1.283 % AR · above range | 0.03 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.28 % AR · in range | 0.72 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.75 % AR · in range | 0.7 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.61 % AR · in range | 0.25 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.58 % AR · in range | 1.45 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.42 % AR · in range | 1.06 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 1.17 % AR · in range | 0.3 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.82 · below range | 3.07 · in range(improved) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 139 specii · in range | 136 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 689 CPM · in range | 738 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1127 CPM · in range | 1204 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 399 CPM · in range | 393 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 139 CPM · in range | 90 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 497 CPM · below range | 530 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 317 CPM · below range | 252 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 2742 CPM · in range | 4068 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 2588 CPM · in range | 2660 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 4126 CPM · in range | 3444 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 4070 CPM · in range | 4199 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 4009 CPM · in range | 2779 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 2.94 % AR · above range | 2.52 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 157 pb · in range | 225 pb · atypical(worsened) | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 38 /100 · above range | 34 /100 · in range(improved) | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 55 /100 · in range | 57 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 61 /100 · in range | 61 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 82 potriviri/M · present | 75 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 25 potriviri/M · present | 44 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 9 citiri/M · present | 3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 5 citiri/M · present | 7.4 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 9.1 citiri/M · present | 3.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 11 citiri/M · present | 4.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | — | 6.9 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| CYP2D6 | 2.94 OR · risk variant | 1.72 OR · risk variant | expected reference genotype | Expected exposure |
| MTHFR | 2.67 OR · risk variant | 2.72 OR · risk variant | expected reference genotype | Reduced folate turnover |