Patient P-02111
Synthetic patientMETA-24 · Day 176 · 55–64 · M · baseline S20Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
70%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S20
- Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 15.
Primary contributors, last 14 days
- Inflammatory activity+7
- Treatment adherence-7
- GI instability+5
- Toxicity-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
70%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 88% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable26 min
stable · +0.2 vs previous 14 d
Sleep duration
Wearable7.3 h
improving · +0.4 vs previous 14 d
Energy level
Daily log2.2/10
improving · +0.5 vs previous 14 d
Steps
Wearable2,888
improving · +306 vs previous 14 d
GI burden
Companion70.3/100
improving · -6.0 vs previous 14 d
Adherence
Companion64.8 %
stable · -2.1 vs previous 14 d
Sleep quality
Wearable38.9/100
improving · +9.0 vs previous 14 d
Glucose, CGM daily mean
CGM138 mg/dL
improving · -7.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 28 from the failing basin, 74 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 65 similar · onset 8 d · confidence 66%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 71%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 71%
- More proteinGI -4.8 next day on high-intake days · n 20
Would not help
- Keep fat lowGI +4.7 next day on high-intake days · n 20
- Keep histamine lowGI +4.5 next day on high-intake days · n 28
- Keep alcohol lowGI +4.2 next day on high-intake days · n 17
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.8supporter · 95%
- Dietary fat load+4.7detractor · 95%
- Histamine load+4.5detractor · 95%
- Alcohol+4.2detractor · 95%
- Simple carbohydrates+3.9detractor · 95%
- Ultra-processed food+3.1detractor · 88%
- Caffeine+0.7no signal · 16%
- Insoluble fibre+0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 70 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 68
- WearableHRV 22 ms, trending down
- Autonomic recovery ↑45
- WearableResting HR 87 bpm
- Wearable2,888 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 54
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.8 · butyrate capacity 30/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 19 ms
- Sleep
- 7.0 h
- Steps
- 4,023
- Resting HR
- 85 bpm
Daily log: GI score 70, nutritional resilience 31, adherence 65.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02151 | 50% | S04 | CR-01 | improved | 49 |
| P-02025 | 43% | S15 | CR-01 | improved | 61 |
| P-02094 | 38% | S14 | NP-02 | improved | 53 |
| P-02165 | 38% | S14 | ME-01 | improved | 59 |
| P-02648 | 38% | S14 | SC-12 | improved | 47 |
| P-02132 | 37% | S14 | SC-12 | improved | 40 |
| P-02348 | 37% | S14 | GI-04 | improved | 49 |
| P-02508 | 37% | S14 | ME-01 | improved | 51 |
| P-02057 | 36% | S14 | GI-04 | improved | 47 |
| P-02236 | 36% | S14 | GI-04 | improved | 45 |
| P-02297 | 36% | S02 | NP-02 | improved | 49 |
| P-02320 | 36% | S14 | NP-02 | improved | 50 |