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Patient P-02194

Synthetic patientMETA-24 · Day 169 · 55–64 · M · baseline S03Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S03
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • Inflammatory activity-10
  • Nutritional resilience+10
  • GI instability-4
  • Toxicity-4
  • Treatment adherence-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    16 min
    worsening · -5.9 vs previous 14 d
    Sleep duration
    Wearable
    7.2 h
    stable · -0.2 vs previous 14 d
    Energy level
    Daily log
    5.4/10
    worsening · -0.4 vs previous 14 d
    Steps
    Wearable
    2,635
    worsening · -719 vs previous 14 d
    GI burden
    Companion
    23.1/100
    worsening · +5.9 vs previous 14 d
    Adherence
    Companion
    91.9 %
    stable · -1.3 vs previous 14 d
    Sleep quality
    Wearable
    44.5/100
    stable · -2.1 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    121 mg/dL
    stable · +0.4 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 74 from the failing basin, 13 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein (supports)
      perturbation · steering +2.5
    • Protein
      supporter · GI -1.5 next day
    Main detractors to watch
    • Rapid metabolizer
      hidden · steering -8
    • Low microbial diversity
      hidden · steering -7.7
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Simple carbohydrates
      detractor · GI +2.1 next day
    • Ultra-processed food
      detractor · GI +1.7 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Simple carbohydrates
      +2.1detractor · 95%
    • Ultra-processed food
      +1.7detractor · 75%
    • Protein
      -1.5supporter · 58%
    • Insoluble fibre
      +0.6no signal · 27%
    • Histamine load
      +0.4no signal · 15%
    • Alcohol
      +0.3no signal · 15%
    • Dietary fat load
      +0.2no signal · 15%
    • Caffeine
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling ↓60
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 38 ms, trending down
    • Autonomic recovery ↑45
      • WearableResting HR 77 bpm
      • Wearable2,635 steps/day
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Rapid metabolizer
      Expected exposure
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 2.9 · butyrate capacity 48/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    35 ms
    Sleep
    7.3 h
    Steps
    2,925
    Resting HR
    77 bpm
    Daily log: GI score 23, nutritional resilience 68, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0223539%S14DT-01improved50
    P-0248539%S05HY-01improved63
    P-0264539%S02HY-01improved56