Patient P-02224
Synthetic patientMETA-24 · Day 172 · 45–54 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
82%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 47 NP-02 recommended — Dietary Support Protocol NP-02
- Day 48 Patient accepted — Started NP-02 in the companion
- Day 58 No meaningful change — Dietary Support Protocol NP-02
- Day 69 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 73 GI-04 recommended — GI Support Protocol GI-04
- Day 74 Patient accepted — Started GI-04 in the companion
- Day 82 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 69.
Primary contributors, last 14 days
- Inflammatory activity+8
- Toxicity+5
- Nutritional resilience-4
- GI instability+2
What helped?
- Dietary Support Protocol NP-02Day 47Result: no meaningful change
- GI Support Protocol GI-04Day 73Result: no meaningful change
LIFE OS recommendation
Monitoring Escalation ME-01
82%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable35 min
improving · +1.4 vs previous 14 d
Sleep duration
Wearable6.5 h
stable · +0.0 vs previous 14 d
Energy level
Daily log2.3/10
worsening · -0.2 vs previous 14 d
Steps
Wearable3,204
improving · +134 vs previous 14 d
GI burden
Companion64.8/100
improving · -10.8 vs previous 14 d
Adherence
Companion43.2 %
worsening · -2.3 vs previous 14 d
Sleep quality
Wearable28.3/100
improving · +2.4 vs previous 14 d
Glucose, CGM daily mean
CGM151 mg/dL
stable · -3.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 9 from the failing basin, 80 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 70%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 70%
- CR-01 Clinician Review100% improved among 6 similar · onset 5 d · confidence 70%
- More proteinGI -5.2 next day on high-intake days · n 24
- More alcoholGI -3.8 next day on high-intake days · n 12
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +5.4 next day on high-intake days · n 27
- Keep ultra-processed lowGI +4.8 next day on high-intake days · n 22
- Keep simple carbs lowGI +4.6 next day on high-intake days · n 10
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.4detractor · 95%
- Protein-5.2supporter · 95%
- Ultra-processed food+4.8detractor · 95%
- Simple carbohydrates+4.6detractor · 95%
- Alcohol-3.8supporter · 78%
- Caffeine+2.1no signal · 46%
- Histamine load+1.7no signal · 35%
- Insoluble fibre+0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 68
- WearableHRV 36 ms, trending down
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 65 and rising
- Drug metabolism and exposure ↑20
- BloodToxicity index 56
- Autonomic recovery ↑20
- Wearable3,204 steps/day
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.5 · butyrate capacity 30/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 34 ms
- Sleep
- 6.6 h
- Steps
- 3,392
- Resting HR
- 68 bpm
Daily log: GI score 65, nutritional resilience 31, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02059 | 48% | S03 | SC-12 | improved | 41 |
| P-02514 | 48% | S05 | ME-01 | improved | 44 |
| P-02546 | 46% | S20 | NP-02 | improved | 40 |
| P-02571 | 43% | S11 | ME-01 | improved | 43 |
| P-02628 | 43% | S14 | SC-12 | improved | 47 |
| P-02132 | 42% | S14 | SC-12 | improved | 40 |
| P-02146 | 42% | S14 | ME-01 | improved | 33 |
| P-02172 | 41% | S02 | ME-01 | improved | 36 |
| P-02348 | 41% | S14 | GI-04 | improved | 49 |
| P-02582 | 41% | S14 | ME-01 | improved | 45 |
| P-02320 | 40% | S14 | NP-02 | improved | 50 |
| P-02326 | 40% | S18 | NP-02 | improved | 44 |