DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
37/100
vs baseline (day 0)
-4
5 improved · 1 worsened
synthetic signature · consistent with this patient's biology
- 2 opportunists above range: Escherichia coli, Clostridioides difficile
- 2 keystone species absent
- 4 resistance genes
- Tissue recycling index 36
Pathogens / opportunists2/5
Keystone species2/8
↓ from 3
Diversity0/2
↓ from 1
Metabolic modules0/4
Vitamin synthesis2/7
Oral translocation1/1
Host DNA0/1
Tissue recycling1/1
↑ from 0
Central mechanisms0/2
Virulence factors2/2
↓ from 3
Antibiotic resistance genes4/4
↓ from 6
Genetic predisposition2/2
Opportunists above range
Escherichia coli 11.584% AR
Clostridioides difficile 1.158% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 3.17 · butyrate 739 CPM · SCFA 1178
2 vitamins below
Host & mechanisms
tissue recycling 36/100
oral translocation 2.66% AR
4 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 14.612 % AR · above range | 11.584 % AR · above range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.008 % AR · in range | 0.188 % AR · in range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 0.198 % AR · in range | 0.294 % AR · in range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.053 % AR · in range | 0.076 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 1.461 % AR · above range | 1.158 % AR · above range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0 % AR · absent | 1.04 % AR · in range(improved) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 1.06 % AR · in range | 1.5 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 1.4 % AR · in range | 0.84 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 1.17 % AR · in range | 1.21 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.19 % AR · in range | 0.81 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.92 % AR · in range | 0.84 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.84 · below range | 3.17 · in range(improved) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 132 specii · in range | 134 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 674 CPM · in range | 739 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1095 CPM · in range | 1178 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 373 CPM · in range | 402 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 95 CPM · in range | 136 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 400 CPM · below range | 205 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 392 CPM · below range | 182 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 4393 CPM · in range | 3345 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3865 CPM · in range | 2982 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 4448 CPM · in range | 3257 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3883 CPM · in range | 2836 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 2646 CPM · in range | 3854 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 3.34 % AR · above range | 2.66 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 162 pb · in range | 164 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 34 /100 · in range | 36 /100 · above range(worsened) | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 59 /100 · in range | 53 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 57 /100 · in range | 56 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 3
| fimD outer membrane usher | 67 potriviri/M · present | 35 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 56 potriviri/M · present | 64 potriviri/M · present | expected absent | Virulence factor detected. |
| irp2 yersiniabactin synthetase | 34 potriviri/M · present | resolved(resolved) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 6
| sul1 | 6.6 citiri/M · present | 8.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 10.3 citiri/M · present | 10.7 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 2.5 citiri/M · present | 2.5 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 9.8 citiri/M · present | 3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 6.9 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
| dfrA1 | 7.6 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| CYP2D6 | 1.72 OR · risk variant | 1.82 OR · risk variant | expected reference genotype | Expected exposure |
| GLP1R | 3.06 OR · risk variant | 2.76 OR · risk variant | expected reference genotype | Altered receptor sensitivity |