DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
24/100
vs baseline (day 0)
+4
3 improved · 2 worsened
synthetic signature · consistent with this patient's biology
- 2 opportunists above range: Escherichia coli, Klebsiella pneumoniae
- 1 keystone species absent
- 2 resistance genes
- Host DNA fragmentation atypical
Pathogens / opportunists2/5
↓ from 3
Keystone species1/8
Diversity0/2
Metabolic modules0/4
Vitamin synthesis1/7
Oral translocation0/1
Host DNA1/1
↑ from 0
Tissue recycling0/1
Central mechanisms0/2
Virulence factors1/1
Antibiotic resistance genes2/2
↓ from 3
Genetic predisposition2/2
Opportunists above range
Escherichia coli 6.912% AR
Klebsiella pneumoniae 2.073% AR
Keystone species absent
Akkermansia muciniphila
Capacity
Shannon 3.43 · butyrate 800 CPM · SCFA 1313
1 vitamins below
Host & mechanisms
host DNA fragmentation atypical
tissue recycling 25/100
oral translocation 1.61% AR
2 resistance genes · 1 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 5.524 % AR · above range | 6.912 % AR · above range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.041 % AR · in range | 2.073 % AR · above range(worsened) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 0.153 % AR · in range | 0.17 % AR · in range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.552 % AR · above range | 0.032 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.552 % AR · above range | 0.025 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0.19 % AR · in range | 0.73 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.75 % AR · in range | 1.03 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.93 % AR · in range | 0.88 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 1.22 % AR · in range | 1.17 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.14 % AR · in range | 0.21 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.32 % AR · in range | 0.8 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.78 % AR · in range | 0.45 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 3.37 · in range | 3.43 · in range | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 161 specii · in range | 145 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 842 CPM · in range | 800 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1312 CPM · in range | 1313 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 464 CPM · in range | 456 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 105 CPM · in range | 119 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 197 CPM · below range | 404 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 3503 CPM · in range | 2876 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 3395 CPM · in range | 3936 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3401 CPM · in range | 4308 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 2934 CPM · in range | 4412 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 4222 CPM · in range | 3747 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 3374 CPM · in range | 3917 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 1.29 % AR · in range | 1.61 % AR · in range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 160 pb · in range | 208 pb · atypical(worsened) | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 28 /100 · in range | 25 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 48 /100 · in range | 55 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 50 /100 · in range | 54 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 1
| fimD outer membrane usher | 99 potriviri/M · present | 68 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 3
| sul1 | 5.6 citiri/M · present | 9.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 1.3 citiri/M · present | 7.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 4.9 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| FUT2 | 3.41 OR · risk variant | 2.48 OR · risk variant | expected reference genotype | Reduced mucosal fucosylation |
| CYP2D6 | 1.51 OR · risk variant | 3.43 OR · risk variant | expected reference genotype | Higher exposure at standard dose |