Patient P-02318
Synthetic patientMETA-24 · Day 99 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
65%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 71 GI-04 recommended — GI Support Protocol GI-04
- Day 72 Patient accepted — Started GI-04 in the companion
- Day 75 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 80 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 75.
Primary contributors, last 14 days
- Treatment adherence-17
- Toxicity+5
- Inflammatory activity-4
- Nutritional resilience-2
What helped?
- GI Support Protocol GI-04Day 71Result: no meaningful change
LIFE OS recommendation
Monitoring Escalation ME-01
86%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable52 min
worsening · -5.0 vs previous 14 d
Sleep duration
Wearable6.2 h
stable · -0.2 vs previous 14 d
Energy level
Daily log2.7/10
worsening · -0.8 vs previous 14 d
Steps
Wearable6,319
worsening · -692 vs previous 14 d
GI burden
Companion63.8/100
worsening · +13.0 vs previous 14 d
Adherence
Companion71.5 %
worsening · -13.4 vs previous 14 d
Sleep quality
Wearable25.6/100
worsening · -3.5 vs previous 14 d
Glucose, CGM daily mean
CGM153 mg/dL
stable · +3.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 41 from the failing basin, 59 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 41 similar · onset 3 d · confidence 74%
- SC-12 Supportive Compound70% improved among 27 similar · onset 6 d · confidence 74%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 74%
- More proteinGI -4.7 next day on high-intake days · n 21
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- Keep fat lowGI +4.6 next day on high-intake days · n 19
- Keep alcohol lowGI +3.7 next day on high-intake days · n 21
- Keep ultra-processed lowGI +3.3 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.7supporter · 95%
- Dietary fat load+4.6detractor · 95%
- Alcohol+3.7detractor · 95%
- Ultra-processed food+3.3detractor · 95%
- Simple carbohydrates+1.8no signal · 45%
- Insoluble fibre+0.5no signal · 15%
- Histamine load+0.4no signal · 15%
- Caffeine0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 25/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 56
- WearableHRV 17 ms, trending down
- Autonomic recovery ↓45
- WearableResting HR 80 bpm
- WearableShort sleep window
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 64 and rising
- Drug metabolism and exposure ↑20
- BloodToxicity index 45
DNA
Fictional pharmacogenomic panel
- CYP2D6 Rapid metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.3 · butyrate capacity 25/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 19 ms
- Sleep
- 5.8 h
- Steps
- 5,505
- Resting HR
- 79 bpm
Daily log: GI score 64, nutritional resilience 38, adherence 72.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 22% | S06 | BR-03 | no change | 64 |
| P-02151 | 30% | S04 | CR-01 | improved | 49 |
| P-02054 | 28% | S01 | CR-01 | improved | 57 |
| P-02233 | 28% | S16 | CR-01 | improved | 66 |
| P-02025 | 27% | S15 | CR-01 | improved | 61 |
| P-02009 | 26% | S08 | CR-01 | improved | 64 |
| P-02154 | 22% | S16 | CR-01 | improved | 57 |
| P-02354 | 21% | S01 | CR-01 | improved | 78 |
| P-02491 | 22% | S09 | DT-01 | no change | 65 |
| P-02395 | 21% | S12 | DT-01 | improved | 57 |
| P-02417 | 21% | S18 | DT-01 | no change | 55 |
| P-02126 | 20% | S16 | DT-01 | improved | 59 |