Patient P-02455
Therapy response
Stable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
8%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S09
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 DT-01 recommended — Dosing / Timing Recommendation DT-01
- Day 23 Patient accepted — Started DT-01 in the companion
- Day 28 GI symptom burden −15% vs expected — Dosing / Timing Recommendation DT-01
- Day 34 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- GI instability-12
- Nutritional resilience+9
- Inflammatory activity-2
- Toxicity+2
What helped?
- Dosing / Timing Recommendation DT-01Day 22Result: symptom burden −15%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 42/100
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 38 ms, trending down
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 42/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 7.3 h
- Steps
- 4,805
- Resting HR
- 61 bpm
Daily log: GI score 14, nutritional resilience 69, adherence 94.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02494 | 56% | S09 | GI-04 | improved | 47 |
| P-02058 | 54% | S05 | GI-04 | no change | 48 |
| P-02513 | 53% | S16 | GI-04 | no change | 46 |
| P-02351 | 52% | S16 | — | — | 51 |
| P-02033 | 51% | S06 | GI-04 | improved | 51 |
| P-02169 | 51% | S17 | — | — | 43 |
| P-02336 | 51% | S20 | — | — | 50 |
| P-02070 | 50% | S11 | — | — | 55 |
| P-02448 | 50% | S10 | — | — | 52 |
| P-02330 | 49% | S15 | DT-01 | no change | 57 |
| P-02355 | 49% | S09 | GI-04 | improved | 55 |
| P-02391 | 49% | S19 | HY-01 | improved | 53 |