Patient P-02355

Synthetic patientMETA-24 · Day 176 · 35–44 · F · baseline S09Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Improving

GI state

Favorable

Inflammatory state

Improving

Nutritional resilience

Declining

Discontinuation risk

12%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S09
Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 GI-04 recommended — GI Support Protocol GI-04
Day 23 Patient accepted — Started GI-04 in the companion
Day 31 GI symptom burden −15% vs expected — GI Support Protocol GI-04
Day 37 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days

Nutritional resilience-8
Inflammatory activity-7
Toxicity-5
GI instability+2

What helped?

GI Support Protocol GI-04Day 22
Result: symptom burden −15%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

50 min

stable · +0.7 vs previous 14 d

Sleep duration

Wearable

7.3 h

stable · +0.0 vs previous 14 d

Energy level

Daily log

7.1/10

worsening · -0.4 vs previous 14 d

Steps

Wearable

4,705

worsening · -272 vs previous 14 d

GI burden

Companion

11.1/100

worsening · +5.4 vs previous 14 d

Adherence

Companion

90.6 %

stable · +2.1 vs previous 14 d

Sleep quality

Wearable

57.4/100

worsening · -3.2 vs previous 14 d

Glucose, CGM daily mean

CGM

127 mg/dL

stable · +1.3 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 81 from the failing basin, 24 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +12
GI Support Protocol GI-04
intervention · steering +10.1
Protein
supporter · GI -6.2 next day

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
Simple carbohydrates
perturbation · steering -10.3
Dietary fat load
perturbation · steering -9
Low microbial diversity
hidden · steering -7.7
Dietary fat load
detractor · GI +5.6 next day
Simple carbohydrates
detractor · GI +5.5 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-6.2supporter · 95%
Dietary fat load
+5.6detractor · 95%
Simple carbohydrates
+5.5detractor · 95%
Ultra-processed food
+4.4detractor · 95%
Caffeine
+2.7no signal · 53%
Insoluble fibre
-1.3no signal · 26%
Alcohol
-1.3no signal · 30%
Histamine load
-1.2no signal · 28%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.6 · butyrate capacity 29/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 39 ms
Sleep: 7.4 h
Steps: 5,189
Resting HR: 64 bpm

Daily log: GI score 11, nutritional resilience 65, adherence 91.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02070	51%	S11	—	—	55
P-02126	51%	S16	DT-01	improved	59
P-02500	50%	S14	GI-04	no change	58
P-02219	49%	S13	—	—	60
P-02455	49%	S09	DT-01	improved	50
P-02501	49%	S14	—	—	55
P-02339	48%	S03	DT-01	improved	50
P-02513	48%	S16	GI-04	no change	46
P-02030	47%	S15	—	—	56
P-02033	47%	S06	GI-04	improved	51
P-02200	47%	S13	—	—	47
P-02235	47%	S14	DT-01	improved	50