Patient P-02359
Synthetic patientMETA-24 · Day 180 · 35–44 · F · baseline S15Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
71%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S15
- Day 21 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 21.
Primary contributors, last 14 days
- Toxicity-18
- GI instability+10
- Inflammatory activity-8
- Nutritional resilience+5
- Treatment adherence+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
66%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 88% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable50 min
worsening · -4.4 vs previous 14 d
Sleep duration
Wearable6.1 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log2.7/10
worsening · -0.7 vs previous 14 d
Steps
Wearable5,026
worsening · -421 vs previous 14 d
GI burden
Companion62.3/100
worsening · +9.7 vs previous 14 d
Adherence
Companion65.7 %
stable · +0.6 vs previous 14 d
Sleep quality
Wearable27.9/100
worsening · -5.9 vs previous 14 d
Glucose, CGM daily mean
CGM155 mg/dL
stable · +4.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 38 from the failing basin, 59 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 65 similar · onset 8 d · confidence 62%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 72%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 72%
- More proteinGI -4.7 next day on high-intake days · n 19
Would not help
- Keep fat lowGI +6.8 next day on high-intake days · n 16
- Keep ultra-processed lowGI +6.5 next day on high-intake days · n 18
- Keep simple carbs lowGI +5.2 next day on high-intake days · n 24
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.8detractor · 95%
- Ultra-processed food+6.5detractor · 95%
- Simple carbohydrates+5.2detractor · 95%
- Protein-4.7supporter · 95%
- Caffeine-1.7no signal · 22%
- Insoluble fibre+1no signal · 21%
- Alcohol+0.9no signal · 19%
- Histamine load+0.7no signal · 18%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 56
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 62 and rising
- WearableSleep 6.1 h, below personal baseline
- Drug metabolism and exposure ↑20
- BloodToxicity index 54
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.1 · butyrate capacity 29/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 45 ms
- Sleep
- 5.4 h
- Steps
- 5,330
- Resting HR
- 72 bpm
Daily log: GI score 62, nutritional resilience 40, adherence 66.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02054 | 37% | S01 | CR-01 | improved | 57 |
| P-02018 | 33% | S01 | GI-04 | improved | 46 |
| P-02410 | 32% | S01 | GI-04 | improved | 55 |
| P-02409 | 28% | S01 | SC-12 | no change | 54 |
| P-02307 | 21% | S01 | — | — | 55 |
| P-02550 | 21% | S01 | — | — | 70 |
| P-02598 | 21% | S01 | — | — | 53 |
| P-02437 | 20% | S01 | — | — | 64 |
| P-02217 | 19% | S01 | — | — | 61 |
| P-02276 | 19% | S01 | — | — | 57 |
| P-02424 | 19% | S01 | — | — | 62 |
| P-02297 | 30% | S02 | NP-02 | improved | 49 |