Patient P-02359

Synthetic patientMETA-24 · Day 180 · 35–44 · F · baseline S15Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Improving

GI state

Unstable

Inflammatory state

Improving

Nutritional resilience

Unstable

Discontinuation risk

71%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S15
Day 21 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 21.

Primary contributors, last 14 days

Toxicity-18
GI instability+10
Inflammatory activity-8
Nutritional resilience+5
Treatment adherence+2

What helped?

No interventions yet.

LIFE OS recommendation

GI Support Protocol GI-04

66%

probability of meaningful tolerance improvement

284 similar trajectories
88% showed improvement
median effect visible after 8 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

50 min

worsening · -4.4 vs previous 14 d

Sleep duration

Wearable

6.1 h

worsening · -0.3 vs previous 14 d

Energy level

Daily log

2.7/10

worsening · -0.7 vs previous 14 d

Steps

Wearable

5,026

worsening · -421 vs previous 14 d

GI burden

Companion

62.3/100

worsening · +9.7 vs previous 14 d

Adherence

Companion

65.7 %

stable · +0.6 vs previous 14 d

Sleep quality

Wearable

27.9/100

worsening · -5.9 vs previous 14 d

Glucose, CGM daily mean

CGM

155 mg/dL

stable · +4.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 38 from the failing basin, 59 from restoration.

Would help

GI-04 GI Support Protocol
75% improved among 65 similar · onset 8 d · confidence 62%
ME-01 Monitoring Escalation
100% improved among 42 similar · onset 3 d · confidence 72%
NP-02 Dietary Support Protocol
59% improved among 32 similar · onset 10 d · confidence 72%
More protein
GI -4.7 next day on high-intake days · n 19

Would not help

Keep fat low
GI +6.8 next day on high-intake days · n 16
Keep ultra-processed low
GI +6.5 next day on high-intake days · n 18
Keep simple carbs low
GI +5.2 next day on high-intake days · n 24

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+6.8detractor · 95%
Ultra-processed food
+6.5detractor · 95%
Simple carbohydrates
+5.2detractor · 95%
Protein
-4.7supporter · 95%
Caffeine
-1.7no signal · 22%
Insoluble fibre
+1no signal · 21%
Alcohol
+0.9no signal · 19%
Histamine load
+0.7no signal · 18%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
Inflammatory signalling ↓50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 56
Mucosal barrier integrity ↓30
- Daily logGI symptom score 62 and rising
- WearableSleep 6.1 h, below personal baseline
Drug metabolism and exposure ↑20
- BloodToxicity index 54
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 2.1 · butyrate capacity 29/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 45 ms
Sleep: 5.4 h
Steps: 5,330
Resting HR: 72 bpm

Daily log: GI score 62, nutritional resilience 40, adherence 66.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Track each bowel movement today: time, stool form, urgency, overnight waking
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
Electrolyte solution, one sachet after any loose stool
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02025	39%	S15	CR-01	improved	61
P-02054	37%	S01	CR-01	improved	57
P-02398	37%	S06	GI-04	improved	63
P-02151	36%	S04	CR-01	improved	49
P-02154	36%	S16	CR-01	improved	57
P-02316	34%	S14	GI-04	improved	51
P-02516	34%	S14	SC-12	improved	51
P-02535	34%	S14	SC-12	improved	50
P-02009	33%	S08	CR-01	improved	64
P-02018	33%	S01	GI-04	improved	46
P-02094	33%	S14	NP-02	improved	53
P-02233	33%	S16	CR-01	improved	66