Patient P-02391
Therapy response
Stable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
6%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S19
- Day 17 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 HY-01 recommended — Hydration Protocol HY-01
- Day 23 Patient accepted — Started HY-01 in the companion
- Day 27 GI symptom burden −17% vs expected — Hydration Protocol HY-01
- Day 33 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 17.
Primary contributors, last 14 days
- GI instability-24
- Inflammatory activity-14
- Nutritional resilience+10
- Toxicity-9
- Treatment adherence-8
What helped?
- Hydration Protocol HY-01Day 22Result: symptom burden −17%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 28/100
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 28/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 37 ms
- Sleep
- 7.4 h
- Steps
- 9,535
- Resting HR
- 71 bpm
Daily log: GI score 7, nutritional resilience 70, adherence 88.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02070 | 49% | S11 | — | — | 55 |
| P-02455 | 49% | S09 | DT-01 | improved | 50 |
| P-02494 | 47% | S09 | GI-04 | improved | 47 |
| P-02033 | 46% | S06 | GI-04 | improved | 51 |
| P-02169 | 46% | S17 | — | — | 43 |
| P-02336 | 46% | S20 | — | — | 50 |
| P-02513 | 46% | S16 | GI-04 | no change | 46 |
| P-02602 | 45% | S20 | HY-01 | improved | 52 |
| P-02058 | 44% | S05 | GI-04 | no change | 48 |
| P-02330 | 44% | S15 | DT-01 | no change | 57 |
| P-02500 | 44% | S14 | GI-04 | no change | 58 |
| P-02501 | 44% | S14 | — | — | 55 |