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Patient P-02391

Synthetic patientMETA-24 · Day 179 · 75+ · F · baseline S19Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
6%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S19
  2. Day 17 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 HY-01 recommended — Hydration Protocol HY-01
  4. Day 23 Patient accepted — Started HY-01 in the companion
  5. Day 27 GI symptom burden −17% vs expected — Hydration Protocol HY-01
  6. Day 33 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days
  • GI instability-24
  • Inflammatory activity-14
  • Nutritional resilience+10
  • Toxicity-9
  • Treatment adherence-8

What helped?

  • Hydration Protocol HY-01Day 22
    Result: symptom burden −17%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
67 min
improving · +4.4 vs previous 14 d
Sleep duration
Wearable
8.2 h
stable · +0.2 vs previous 14 d
Energy level
Daily log
7.5/10
improving · +0.6 vs previous 14 d
Steps
Wearable
7,840
improving · +425 vs previous 14 d
GI burden
Companion
7.1/100
improving · -9.0 vs previous 14 d
Adherence
Companion
87.8 %
worsening · -5.5 vs previous 14 d
Sleep quality
Wearable
67/100
improving · +5.6 vs previous 14 d
Glucose, CGM daily mean
CGM
120 mg/dL
improving · -6.0 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 87 from the failing basin, 29 from restoration.

Good elements to keep
  • Hydration Protocol HY-01
    intervention · steering +11.1
  • Protein (supports)
    perturbation · steering +10.1
  • Protein
    supporter · GI -5.5 next day
Main detractors to watch
  • Low butyrate capacity
    hidden · steering -17.5
  • FUT2 non-secretor
    hidden · steering -10.6
  • Histamine load
    perturbation · steering -8
  • Low microbial diversity
    hidden · steering -7.7
  • Dietary fat load
    detractor · GI +4.7 next day
  • Histamine load
    detractor · GI +4.6 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -5.5supporter · 95%
  • Dietary fat load
    +4.7detractor · 95%
  • Histamine load
    +4.6detractor · 95%
  • Simple carbohydrates
    +4.3detractor · 95%
  • Ultra-processed food
    +3.8detractor · 95%
  • Caffeine
    -1.3no signal · 32%
  • Alcohol
    -1.1no signal · 27%
  • Insoluble fibre
    -1no signal · 21%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓60
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Butyrate / short-chain fatty acid production ↓60
    • MicrobiomeButyrate capacity 28/100
    • MicrobiomeF. prausnitzii depleted
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 28/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
37 ms
Sleep
7.4 h
Steps
9,535
Resting HR
71 bpm
Daily log: GI score 7, nutritional resilience 70, adherence 88.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0207049%S11——55
P-0245549%S09DT-01improved50
P-0249447%S09GI-04improved47
P-0203346%S06GI-04improved51
P-0216946%S17——43
P-0233646%S20——50
P-0251346%S16GI-04no change46
P-0260245%S20HY-01improved52
P-0205844%S05GI-04no change48
P-0233044%S15DT-01no change57
P-0250044%S14GI-04no change58
P-0250144%S14——55