Patient P-02421

Synthetic patientMETA-24 · Day 132 · 55–64 · F · baseline S04Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S04
Day 30 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 30.

Primary contributors, last 14 days

Toxicity-10
Nutritional resilience+4
Treatment adherence-4
Inflammatory activity-3
GI instability-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

56 min

improving · +3.4 vs previous 14 d

Sleep duration

Wearable

7.1 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

5.9/10

improving · +0.5 vs previous 14 d

Steps

Wearable

5,264

improving · +328 vs previous 14 d

GI burden

Companion

19.1/100

improving · -5.1 vs previous 14 d

Adherence

Companion

93.5 %

stable · +2.2 vs previous 14 d

Sleep quality

Wearable

56.6/100

worsening · -2.9 vs previous 14 d

Glucose, CGM daily mean

CGM

136 mg/dL

stable · +0.2 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 76 from the failing basin, 15 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +11.3
Butyrate producers intact
hidden · steering +7.5
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -5.7 next day

Main detractors to watch

Enterobacteriaceae elevated
hidden · steering -7.4
Poor-sleep week
perturbation · steering -3
Dietary drift
perturbation · steering -2.6

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.7supporter · 95%
Caffeine
-2.4no signal · 38%
Dietary fat load
+1.1no signal · 19%
Histamine load
-1no signal · 19%
Ultra-processed food
-0.4no signal · 15%
Insoluble fibre
-0.3no signal · 15%
Alcohol
+0.3no signal · 15%
Simple carbohydrates
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity

Microbiome

Shannon diversity 3.7 · butyrate capacity 66/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 45 ms
Sleep: 7.1 h
Steps: 5,185
Resting HR: 66 bpm

Daily log: GI score 19, nutritional resilience 66, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02031	33%	S12	AD-05	improved	47
P-02285	33%	S14	AD-05	no change	39
P-02483	46%	S06	BR-03	no change	64
P-02267	37%	S09	BR-03	no change	45
P-02280	35%	S07	BR-03	no change	50
P-02087	33%	S01	BR-03	no change	40
P-02354	39%	S01	CR-01	improved	78
P-02491	50%	S09	DT-01	no change	65
P-02462	48%	S12	DT-01	improved	65
P-02518	48%	S17	DT-01	improved	68
P-02126	41%	S16	DT-01	improved	59
P-02339	41%	S03	DT-01	improved	50