Patient P-02267

Synthetic patientMETA-24 · Day 123 · 35–44 · M · baseline S09Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S09
Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 108 BR-03 recommended — Behavioural Recommendation BR-03
Day 109 Patient accepted — Started BR-03 in the companion
Day 116 No meaningful change — Behavioural Recommendation BR-03

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days

GI instability-19
Inflammatory activity-16
Nutritional resilience+16
Toxicity-7

What helped?

Behavioural Recommendation BR-03Day 108
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

67 min

improving · +3.6 vs previous 14 d

Sleep duration

Wearable

7.2 h

stable · -0.0 vs previous 14 d

Energy level

Daily log

5.8/10

worsening · -0.3 vs previous 14 d

Steps

Wearable

8,402

improving · +302 vs previous 14 d

GI burden

Companion

12.2/100

worsening · +2.4 vs previous 14 d

Adherence

Companion

93.1 %

stable · -2.2 vs previous 14 d

Sleep quality

Wearable

56.8/100

stable · -1.5 vs previous 14 d

Glucose, CGM daily mean

CGM

130 mg/dL

stable · +2.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 77 from the failing basin, 34 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.9 next day on high-intake days · n 20

Would not help

BR-03 Behavioural Recommendation
already tried, no meaningful change
Keep alcohol low
GI +7.2 next day on high-intake days · n 12
Keep histamine low
GI +5.2 next day on high-intake days · n 20

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+7.2detractor · 95%
Protein
-5.9supporter · 95%
Histamine load
+5.2detractor · 95%
Ultra-processed food
-2.2no signal · 43%
Caffeine
+0.8no signal · 15%
Dietary fat load
+0.4no signal · 15%
Simple carbohydrates
-0.3no signal · 15%
Insoluble fibre
-0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Autonomic recovery ↑25
- WearableResting HR 74 bpm
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 4.2 · butyrate capacity 57/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 38 ms
Sleep: 6.7 h
Steps: 7,631
Resting HR: 76 bpm

Daily log: GI score 12, nutritional resilience 68, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02465	46%	S04	—	—	46
P-02285	45%	S14	AD-05	no change	39
P-02494	45%	S09	GI-04	improved	47
P-02529	45%	S17	—	—	45
P-02455	44%	S09	DT-01	improved	50
P-02585	44%	S03	—	—	50
P-02087	43%	S01	BR-03	no change	40
P-02169	43%	S17	—	—	43
P-02412	43%	S18	—	—	52
P-02239	42%	S04	—	—	50
P-02280	42%	S07	BR-03	no change	50
P-02303	42%	S15	GI-04	improved	48