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Patient P-02447

Synthetic patientMETA-24 · Day 172 · 55–64 · M · baseline S08Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S08
  2. Day 39 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 39.

Primary contributors, last 14 days
  • Toxicity+10
  • Treatment adherence-8
  • Inflammatory activity+5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    19 min
    worsening · -4.4 vs previous 14 d
    Sleep duration
    Wearable
    7.1 h
    stable · -0.1 vs previous 14 d
    Energy level
    Daily log
    6.1/10
    stable · -0.0 vs previous 14 d
    Steps
    Wearable
    1,758
    worsening · -633 vs previous 14 d
    GI burden
    Companion
    14.4/100
    worsening · +3.9 vs previous 14 d
    Adherence
    Companion
    78.3 %
    worsening · -4.6 vs previous 14 d
    Sleep quality
    Wearable
    43.1/100
    worsening · -5.0 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    125 mg/dL
    stable · +3.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 72 from the failing basin, 45 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -4.3 next day on high-intake days · n 22
    Would not help
    • BR-03 Behavioural Recommendation
      only 22% improved among 9 similar
    • Keep alcohol low
      GI +4.3 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      +4.3detractor · 95%
    • Protein
      -4.3supporter · 95%
    • Ultra-processed food
      +2.2no signal · 50%
    • Simple carbohydrates
      -1.5no signal · 31%
    • Caffeine
      -0.8no signal · 19%
    • Dietary fat load
      -0.7no signal · 15%
    • Insoluble fibre
      +0.3no signal · 15%
    • Histamine load
      -0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling 25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    • Autonomic recovery 20
      • Wearable1,758 steps/day
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4 · butyrate capacity 68/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    35 ms
    Sleep
    7.1 h
    Steps
    3,204
    Resting HR
    60 bpm
    Daily log: GI score 14, nutritional resilience 71, adherence 78.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0221426%S08SC-12no change69
    P-0229326%S15HY-01no change68
    P-0209026%S0468
    P-0265826%S0466
    P-0210925%S0466
    P-0209528%S0866
    P-0235825%S1865
    P-0226626%S0365
    P-0204426%S0364
    P-0248326%S06BR-03no change64
    P-0237125%S1664
    P-0221025%S1464