Patient P-02458

Synthetic patientMETA-24 · Day 94 · 35–44 · M · baseline S16Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S16
Day 67 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 67.

Primary contributors, last 14 days

GI instability-33
Nutritional resilience+27
Inflammatory activity-26
Toxicity-24
Treatment adherence-7

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

69 min

improving · +5.0 vs previous 14 d

Sleep duration

Wearable

7.7 h

stable · +0.3 vs previous 14 d

Energy level

Daily log

7.9/10

improving · +1.0 vs previous 14 d

Steps

Wearable

6,909

improving · +675 vs previous 14 d

GI burden

Companion

4.9/100

improving · -21.4 vs previous 14 d

Adherence

Companion

85.6 %

worsening · -3.9 vs previous 14 d

Sleep quality

Wearable

72/100

improving · +10.5 vs previous 14 d

Glucose, CGM daily mean

CGM

126 mg/dL

improving · -7.1 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 95 from the failing basin, 19 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +14.6
Butyrate producers intact
hidden · steering +7.5
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -6.6 next day

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Caffeine
perturbation · steering -11
Antibiotic course
perturbation · steering -4.7
Dietary drift
perturbation · steering -2.6
Caffeine
detractor · GI +6.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-6.6supporter · 95%
Caffeine
+6.3detractor · 95%
Histamine load
+1.4no signal · 22%
Ultra-processed food
-1.4no signal · 26%
Simple carbohydrates
-1.3no signal · 15%
Alcohol
-1.3no signal · 24%
Dietary fat load
+0.4no signal · 15%
Insoluble fibre
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 3.7 · butyrate capacity 81/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 57 ms
Sleep: 7.5 h
Steps: 5,260
Resting HR: 71 bpm

Daily log: GI score 5, nutritional resilience 75, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02285	29%	S14	AD-05	no change	39
P-02031	28%	S12	AD-05	improved	47
P-02483	31%	S06	BR-03	no change	64
P-02267	30%	S09	BR-03	no change	45
P-02282	30%	S01	BR-03	no change	88
P-02280	29%	S07	BR-03	no change	50
P-02462	33%	S12	DT-01	improved	65
P-02491	33%	S09	DT-01	no change	65
P-02518	33%	S17	DT-01	improved	68
P-02586	33%	S18	DT-01	improved	56
P-02218	32%	S01	DT-01	improved	61
P-02126	31%	S16	DT-01	improved	59