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Patient P-02462

Synthetic patientMETA-24 · Day 157 · 55–64 · F · baseline S12Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S12
  2. Day 30 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 55 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 56 Patient accepted — Started DT-01 in the companion
  5. Day 61 GI symptom burden −18% vs expected — Dosing / Timing Recommendation DT-01
  6. Day 67 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 30.

Primary contributors, last 14 days
  • Toxicity-7
  • Inflammatory activity-5
  • GI instability+3
  • Treatment adherence+2

What helped?

  • Dosing / Timing Recommendation DT-01Day 55
    Result: symptom burden −18%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
74 min
improving · +3.6 vs previous 14 d
Sleep duration
Wearable
6.3 h
stable · +0.0 vs previous 14 d
Energy level
Daily log
6.2/10
improving · +0.6 vs previous 14 d
Steps
Wearable
8,567
improving · +506 vs previous 14 d
GI burden
Companion
22.4/100
worsening · +0.9 vs previous 14 d
Adherence
Companion
98.1 %
stable · +0.9 vs previous 14 d
Sleep quality
Wearable
44.3/100
stable · +1.1 vs previous 14 d
Glucose, CGM daily mean
CGM
141 mg/dL
stable · -0.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 75 from the failing basin, 14 from restoration.

Good elements to keep
  • Dosing / Timing Recommendation DT-01
    intervention · steering +23.5
  • Butyrate producers intact
    hidden · steering +7.5
  • Protein (supports)
    perturbation · steering +5.4
  • Daily walks resumed
    perturbation · steering +3.3
  • Protein
    supporter · GI -3.2 next day
Main detractors to watch
  • FUT2 non-secretor
    hidden · steering -10.6
  • Histamine load
    perturbation · steering -7.6
  • Bacteroides fragilis elevated
    hidden · steering -7.4
  • IL6 high-expression variant
    hidden · steering -7.3
  • Histamine load
    detractor · GI +4.6 next day
  • Ultra-processed food
    detractor · GI +3.8 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +4.6detractor · 95%
  • Ultra-processed food
    +3.8detractor · 95%
  • Protein
    -3.2supporter · 95%
  • Alcohol
    +1.7no signal · 40%
  • Insoluble fibre
    +0.7no signal · 17%
  • Caffeine
    +0.6no signal · 15%
  • Simple carbohydrates
    +0.4no signal · 15%
  • Dietary fat load
    0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Inflammatory signalling ↓45
    • DNAIL6 -174 variant raises baseline inflammatory tone
    • MicrobiomeBacteroides fragilis expansion
  • Mucosal barrier integrity ↓30
    • DNAFUT2 non-secretor lowers mucosal fucosylation
  • Butyrate / short-chain fatty acid production ↓25
    • MicrobiomeF. prausnitzii depleted
  • Autonomic recovery ↓20
    • WearableShort sleep window
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • IL6 -174 G/C
    Higher inflammatory tone
  • CYP2D6 Normal metabolizer
    Expected exposure
  • GLP1R rs6923761 A
    Altered receptor sensitivity
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 4.1 · butyrate capacity 63/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
51 ms
Sleep
6.5 h
Steps
8,357
Resting HR
64 bpm
Daily log: GI score 22, nutritional resilience 63, adherence 98.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0254455%S12——57
P-0229053%S12——57
P-0242352%S10——65
P-0249151%S09DT-01no change65
P-0202150%S06——61
P-0219450%S03——67
P-0221050%S14——64
P-0240350%S03——71
P-0255150%S18——64
P-0207749%S20——60
P-0208049%S11——59
P-0221749%S01——61