Patient P-02489

Synthetic patientMETA-24 · Day 123 · 45–54 · F · baseline S09Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Stable

Discontinuation risk

23%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S09
Day 62 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 62.

Primary contributors, last 14 days

Toxicity+12
GI instability-9
Inflammatory activity-5
Treatment adherence-5

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

57 min

worsening · -3.3 vs previous 14 d

Sleep duration

Wearable

5.9 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

4.8/10

worsening · -0.5 vs previous 14 d

Steps

Wearable

6,936

stable · -179 vs previous 14 d

GI burden

Companion

22/100

worsening · +1.9 vs previous 14 d

Adherence

Companion

86.7 %

stable · -1.4 vs previous 14 d

Sleep quality

Wearable

38.4/100

stable · -0.1 vs previous 14 d

Glucose, CGM daily mean

CGM

141 mg/dL

stable · +2.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 73 from the failing basin, 15 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -3.8 next day on high-intake days · n 21

Would not help

Keep caffeine low
GI +3.8 next day on high-intake days · n 18
Keep alcohol low
GI +3.4 next day on high-intake days · n 16

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Caffeine
+3.8detractor · 95%
Protein
-3.8supporter · 95%
Alcohol
+3.4detractor · 95%
Insoluble fibre
+1.8no signal · 36%
Histamine load
-1.3no signal · 31%
Dietary fat load
-0.4no signal · 15%
Simple carbohydrates
+0.2no signal · 15%
Ultra-processed food
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↓20
- WearableShort sleep window
Mucosal barrier integrity ↓10
- WearableSleep 5.9 h, below personal baseline

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose
GLP1R rs6923761 A
Altered receptor sensitivity
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.4 · butyrate capacity 75/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 42 ms
Sleep: 6.0 h
Steps: 6,886
Resting HR: 60 bpm

Daily log: GI score 22, nutritional resilience 55, adherence 87.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02483	42%	S06	BR-03	no change	64
P-02280	34%	S07	BR-03	no change	50
P-02267	32%	S09	BR-03	no change	45
P-02354	35%	S01	CR-01	improved	78
P-02491	41%	S09	DT-01	no change	65
P-02518	40%	S17	DT-01	improved	68
P-02462	38%	S12	DT-01	improved	65
P-02126	35%	S16	DT-01	improved	59
P-02235	35%	S14	DT-01	improved	50
P-02339	35%	S03	DT-01	improved	50
P-02274	34%	S15	DT-01	improved	50
P-02685	33%	S16	DT-01	improved	47