Patient P-02532
Therapy response
Improving
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 65 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 65.
Primary contributors, last 14 days
- GI instability+12
- Inflammatory activity+4
- Nutritional resilience-4
- Treatment adherence+4
- Toxicity+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 87% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable0 min
worsening · -5.4 vs previous 14 d
Sleep duration
Wearable7 h
stable · +0.0 vs previous 14 d
Energy level
Daily log1.8/10
stable · -0.1 vs previous 14 d
Steps
Wearable300
worsening · -608 vs previous 14 d
GI burden
Companion79.9/100
stable · +1.3 vs previous 14 d
Adherence
Companion42.7 %
improving · +2.4 vs previous 14 d
Sleep quality
Wearable32.5/100
improving · +1.5 vs previous 14 d
Glucose, CGM daily mean
CGM154 mg/dL
stable · +1.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 37 from the failing basin, 78 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 63 similar · onset 8 d · confidence 96%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 70%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 70%
- More proteinGI -3.9 next day on high-intake days · n 20
- More alcoholGI -2.3 next day on high-intake days · n 13
Would not help
- Keep fat lowGI +3.4 next day on high-intake days · n 22
- Keep caffeine lowGI +3.4 next day on high-intake days · n 21
- Keep ultra-processed lowGI +3.3 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.9supporter · 95%
- Dietary fat load+3.4detractor · 95%
- Caffeine+3.4detractor · 95%
- Ultra-processed food+3.3detractor · 95%
- Alcohol-2.3supporter · 64%
- Simple carbohydrates+2.2detractor · 73%
- Insoluble fibre-0.5no signal · 17%
- Histamine load+0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 65
- WearableHRV 29 ms, trending down
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 51
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 37/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 85 bpm
- Wearable300 steps/day
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 80 and rising
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 1.9 · butyrate capacity 37/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 27 ms
- Sleep
- 6.9 h
- Steps
- 585
- Resting HR
- 83 bpm
Daily log: GI score 80, nutritional resilience 30, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02157 | 62% | S14 | ME-01 | improved | 55 |
| P-02320 | 49% | S14 | NP-02 | improved | 50 |
| P-02372 | 48% | S14 | ME-01 | improved | 53 |
| P-02571 | 45% | S11 | ME-01 | improved | 43 |
| P-02348 | 43% | S14 | GI-04 | improved | 49 |
| P-02514 | 43% | S05 | ME-01 | improved | 44 |
| P-02628 | 43% | S14 | SC-12 | improved | 47 |
| P-02505 | 42% | S14 | NP-02 | improved | 45 |
| P-02582 | 42% | S14 | ME-01 | improved | 45 |
| P-02014 | 41% | S14 | GI-04 | improved | 48 |
| P-02057 | 40% | S14 | GI-04 | improved | 47 |
| P-02146 | 39% | S14 | ME-01 | improved | 33 |