Patient P-02535
Synthetic patientMETA-24 · Day 169 · 45–54 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Stable
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
92%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 47 NP-02 recommended — Dietary Support Protocol NP-02
- Day 48 Patient accepted — Started NP-02 in the companion
- Day 58 No meaningful change — Dietary Support Protocol NP-02
- Day 66 SC-12 recommended — Supportive Compound SC-12
- Day 67 Patient accepted — Started SC-12 in the companion
- Day 73 GI symptom burden −10% vs expected — Supportive Compound SC-12
- Day 79 Tolerance state changed — Unstable → Improving
- Day 83 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 83.
Primary contributors, last 14 days
- Nutritional resilience+4
- Treatment adherence-2
What helped?
- Dietary Support Protocol NP-02Day 47Result: no meaningful change
- Supportive Compound SC-12Day 66Result: symptom burden −10%
LIFE OS recommendation
GI Support Protocol GI-04
91%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 86% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable6 min
stable · -0.3 vs previous 14 d
Sleep duration
Wearable5 h
stable · -0.1 vs previous 14 d
Energy level
Daily log3/10
stable · +0.1 vs previous 14 d
Steps
Wearable386
worsening · -181 vs previous 14 d
GI burden
Companion56/100
stable · -0.3 vs previous 14 d
Adherence
Companion43.2 %
stable · +0.5 vs previous 14 d
Sleep quality
Wearable18.7/100
stable · +0.3 vs previous 14 d
Glucose, CGM daily mean
CGM146 mg/dL
stable · -1.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 31 from the failing basin, 58 from restoration.
Would help
- GI-04 GI Support Protocol74% improved among 65 similar · onset 8 d · confidence 92%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 73%
- CR-01 Clinician Review100% improved among 6 similar · onset 5 d · confidence 73%
- More proteinGI -5.3 next day on high-intake days · n 20
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep histamine lowGI +7.5 next day on high-intake days · n 20
- Keep fat lowGI +7.2 next day on high-intake days · n 25
- Keep ultra-processed lowGI +6.9 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+7.5detractor · 95%
- Dietary fat load+7.2detractor · 95%
- Ultra-processed food+6.9detractor · 95%
- Simple carbohydrates+5.8detractor · 95%
- Protein-5.3supporter · 95%
- Alcohol+3.2detractor · 67%
- Caffeine-2.6no signal · 46%
- Insoluble fibre+1.8no signal · 29%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 55
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 56 and rising
- WearableSleep 5.0 h, below personal baseline
- Autonomic recovery ↑40
- Wearable386 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 50
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.7 · butyrate capacity 44/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 37 ms
- Sleep
- 5.0 h
- Steps
- 1,001
- Resting HR
- 66 bpm
Daily log: GI score 56, nutritional resilience 42, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02670 | 61% | S14 | SC-12 | improved | 45 |
| P-02320 | 57% | S14 | NP-02 | improved | 50 |
| P-02363 | 57% | S14 | GI-04 | improved | 49 |
| P-02628 | 56% | S14 | SC-12 | improved | 47 |
| P-02348 | 55% | S14 | GI-04 | improved | 49 |
| P-02516 | 55% | S14 | SC-12 | improved | 51 |
| P-02574 | 53% | S14 | ME-01 | improved | 45 |
| P-02693 | 50% | S14 | ME-01 | improved | 41 |
| P-02316 | 49% | S14 | GI-04 | improved | 51 |
| P-02326 | 49% | S18 | NP-02 | improved | 44 |
| P-02401 | 49% | S14 | GI-04 | improved | 49 |
| P-02118 | 48% | S14 | GI-04 | improved | 47 |