Patient P-02544

Synthetic patientMETA-24 · Day 176 · 55–64 · F · baseline S12Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

27%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S12
Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days

Toxicity-17
GI instability+10
Nutritional resilience-3
Treatment adherence-3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

61 min

stable · -0.4 vs previous 14 d

Sleep duration

Wearable

5.6 h

stable · -0.2 vs previous 14 d

Energy level

Daily log

5/10

improving · +0.2 vs previous 14 d

Steps

Wearable

7,435

stable · -51 vs previous 14 d

GI burden

Companion

25.2/100

stable · -0.0 vs previous 14 d

Adherence

Companion

92.5 %

stable · +1.9 vs previous 14 d

Sleep quality

Wearable

27.5/100

stable · -0.2 vs previous 14 d

Glucose, CGM daily mean

CGM

141 mg/dL

stable · +3.5 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 68 from the failing basin, 22 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.8 next day on high-intake days · n 24
More histamine
GI -4.3 next day on high-intake days · n 14

Would not help

Keep caffeine low
GI +5.8 next day on high-intake days · n 21
Keep ultra-processed low
GI +5.2 next day on high-intake days · n 22
Keep simple carbs low
GI +4.8 next day on high-intake days · n 20

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Caffeine
+5.8detractor · 95%
Protein
-5.8supporter · 95%
Ultra-processed food
+5.2detractor · 95%
Simple carbohydrates
+4.8detractor · 95%
Histamine load
-4.3supporter · 95%
Alcohol
-1.7no signal · 33%
Insoluble fibre
+1.1no signal · 22%
Dietary fat load
+0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Autonomic recovery ↑20
- WearableShort sleep window
Mucosal barrier integrity ↓10
- WearableSleep 5.6 h, below personal baseline

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 2.9 · butyrate capacity 68/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 48 ms
Sleep: 5.8 h
Steps: 8,171
Resting HR: 69 bpm

Daily log: GI score 25, nutritional resilience 62, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02462	55%	S12	DT-01	improved	65
P-02620	45%	S01	HY-01	improved	64
P-02518	44%	S17	DT-01	improved	68
P-02538	44%	S02	GI-04	improved	59
P-02082	43%	S12	NP-02	improved	53
P-02235	43%	S14	DT-01	improved	50
P-02645	42%	S02	HY-01	improved	56
P-02033	41%	S06	GI-04	improved	51
P-02037	40%	S04	GI-04	improved	53
P-02147	40%	S13	GI-04	improved	58
P-02274	40%	S15	DT-01	improved	50
P-02339	40%	S03	DT-01	improved	50