Patient P-02571
Therapy response
Stable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S11
- Day 22 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 83 ME-01 recommended — Monitoring Escalation ME-01
- Day 84 Patient accepted — Started ME-01 in the companion
- Day 87 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 22.
Primary contributors, last 14 days
- GI instability+13
- Nutritional resilience-6
- Inflammatory activity+4
What helped?
- Monitoring Escalation ME-01Day 83Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 89% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable0 min
improving · +2.8 vs previous 14 d
Sleep duration
Wearable5.8 h
stable · -0.1 vs previous 14 d
Energy level
Daily log2.2/10
worsening · -0.2 vs previous 14 d
Steps
Wearable568
improving · +349 vs previous 14 d
GI burden
Companion76.5/100
worsening · +7.0 vs previous 14 d
Adherence
Companion42 %
stable · +0.8 vs previous 14 d
Sleep quality
Wearable11.3/100
worsening · -2.3 vs previous 14 d
Glucose, CGM daily mean
CGM151 mg/dL
stable · +2.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 22 from the failing basin, 80 from restoration.
Would help
- GI-04 GI Support Protocol77% improved among 64 similar · onset 8 d · confidence 96%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 76%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 76%
- More proteinGI -5.2 next day on high-intake days · n 13
Would not help
- Keep histamine lowGI +6.3 next day on high-intake days · n 18
- Keep ultra-processed lowGI +6.2 next day on high-intake days · n 18
- Keep simple carbs lowGI +3.9 next day on high-intake days · n 16
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+6.3detractor · 95%
- Ultra-processed food+6.2detractor · 95%
- Protein-5.2supporter · 95%
- Simple carbohydrates+3.9detractor · 82%
- Alcohol+2.8detractor · 56%
- Insoluble fibre+1.5no signal · 31%
- Dietary fat load-0.5no signal · 15%
- Caffeine+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 64
- WearableHRV 23 ms, trending down
- Autonomic recovery ↓65
- WearableResting HR 77 bpm
- Wearable568 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 77 and rising
- WearableSleep 5.8 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 46
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2 · butyrate capacity 48/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 22 ms
- Sleep
- 5.9 h
- Steps
- 1,334
- Resting HR
- 76 bpm
Daily log: GI score 77, nutritional resilience 35, adherence 42.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02146 | 49% | S14 | ME-01 | improved | 33 |
| P-02157 | 46% | S14 | ME-01 | improved | 55 |
| P-02320 | 45% | S14 | NP-02 | improved | 50 |
| P-02514 | 45% | S05 | ME-01 | improved | 44 |
| P-02546 | 45% | S20 | NP-02 | improved | 40 |
| P-02505 | 44% | S14 | NP-02 | improved | 45 |
| P-02582 | 44% | S14 | ME-01 | improved | 45 |
| P-02014 | 43% | S14 | GI-04 | improved | 48 |
| P-02132 | 43% | S14 | SC-12 | improved | 40 |
| P-02172 | 43% | S02 | ME-01 | improved | 36 |
| P-02628 | 43% | S14 | SC-12 | improved | 47 |
| P-02297 | 42% | S02 | NP-02 | improved | 49 |