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Patient P-02587

Synthetic patientMETA-24 · Day 174 · 25–34 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
33%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S14
  2. Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days
  • Nutritional resilience-6
  • Toxicity+3
  • Treatment adherence-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    67 min
    improving · +4.9 vs previous 14 d
    Sleep duration
    Wearable
    6 h
    stable · +0.2 vs previous 14 d
    Energy level
    Daily log
    5.6/10
    improving · +0.3 vs previous 14 d
    Steps
    Wearable
    7,570
    improving · +430 vs previous 14 d
    GI burden
    Companion
    28.3/100
    improving · -12.2 vs previous 14 d
    Adherence
    Companion
    91.7 %
    stable · -3.7 vs previous 14 d
    Sleep quality
    Wearable
    30.2/100
    improving · +5.8 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    140 mg/dL
    stable · -3.1 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading drifting · 66 from the failing basin, 20 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein (supports)
      perturbation · steering +5.9
    • Protein
      supporter · GI -3.6 next day
    Main detractors to watch
    • FUT2 non-secretor
      hidden · steering -10.6
    • Rapid metabolizer
      hidden · steering -8
    • Low microbial diversity
      hidden · steering -7.7
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Histamine load
      detractor · GI +3 next day
    • Ultra-processed food
      detractor · GI +2.9 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -3.6supporter · 95%
    • Histamine load
      +3detractor · 95%
    • Ultra-processed food
      +2.9detractor · 95%
    • Simple carbohydrates
      +2.8detractor · 95%
    • Dietary fat load
      +0.8no signal · 26%
    • Caffeine
      +0.6no signal · 21%
    • Alcohol
      +0.4no signal · 15%
    • Insoluble fibre
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓70
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 6.0 h, below personal baseline
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Inflammatory signalling ↑20
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery ↓20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.9 · butyrate capacity 59/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    43 ms
    Sleep
    6.4 h
    Steps
    6,401
    Resting HR
    67 bpm
    Daily log: GI score 28, nutritional resilience 55, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0251842%S17DT-01improved68
    P-0246241%S12DT-01improved65
    P-0253840%S02GI-04improved59
    P-0269840%S06ME-01improved71
    P-0262039%S01HY-01improved64
    P-0235437%S01CR-01improved78
    P-0203736%S04GI-04improved53
    P-0223536%S14DT-01improved50
    P-0227436%S15DT-01improved50
    P-0229836%S14GI-04improved65
    P-0233936%S03DT-01improved50
    P-0239536%S12DT-01improved57