Patient P-02638
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Improving
Discontinuation risk
18%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S01
- Day 108 BR-03 recommended — Behavioural Recommendation BR-03
- Day 109 Patient accepted — Started BR-03 in the companion
- Day 116 GI symptom burden −12% vs expected — Behavioural Recommendation BR-03
- Day 122 Tolerance state changed — Unstable → Improving
- Day 127 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 127.
Primary contributors, last 14 days
- Inflammatory activity+9
- GI instability+5
- Toxicity+5
- Nutritional resilience+4
- Treatment adherence+4
What helped?
- Behavioural Recommendation BR-03Day 108Result: symptom burden −12%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Autonomic recovery ↓25
- WearableResting HR 76 bpm
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.3 · butyrate capacity 69/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 69 ms
- Sleep
- 7.3 h
- Steps
- 9,083
- Resting HR
- 74 bpm
Daily log: GI score 23, nutritional resilience 70, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02087 | 45% | S01 | BR-03 | no change | 40 |
| P-02465 | 43% | S04 | — | — | 46 |
| P-02112 | 42% | S14 | — | — | 42 |
| P-02412 | 42% | S18 | — | — | 52 |
| P-02267 | 39% | S09 | BR-03 | no change | 45 |
| P-02457 | 39% | S03 | — | — | 54 |
| P-02611 | 39% | S17 | — | — | 44 |
| P-02681 | 39% | S01 | — | — | 51 |
| P-02477 | 38% | S16 | — | — | 53 |
| P-02479 | 38% | S13 | DT-01 | improved | 48 |
| P-02280 | 37% | S07 | BR-03 | no change | 50 |
| P-02285 | 37% | S14 | AD-05 | no change | 39 |