Patient P-02641

Synthetic patientMETA-24 · Day 170 · 25–34 · F · baseline S05Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

33%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S05
Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 DT-01 recommended — Dosing / Timing Recommendation DT-01
Day 23 Patient accepted — Started DT-01 in the companion
Day 28 No meaningful change — Dosing / Timing Recommendation DT-01

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days

Inflammatory activity+16
Nutritional resilience-11
GI instability+10
Treatment adherence-10
Toxicity+7

What helped?

Dosing / Timing Recommendation DT-01Day 22
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

94 min

stable · -2.4 vs previous 14 d

Sleep duration

Wearable

5.5 h

improving · +0.3 vs previous 14 d

Energy level

Daily log

5.5/10

stable · -0.1 vs previous 14 d

Steps

Wearable

9,828

worsening · -389 vs previous 14 d

GI burden

Companion

24.3/100

worsening · +1.5 vs previous 14 d

Adherence

Companion

85.1 %

worsening · -5.8 vs previous 14 d

Sleep quality

Wearable

31.5/100

stable · +1.1 vs previous 14 d

Glucose, CGM daily mean

CGM

142 mg/dL

stable · -2.0 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 59 from the failing basin, 36 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.4 next day on high-intake days · n 24

Would not help

DT-01 Dosing / Timing Recommendation
already tried, no meaningful change
BR-03 Behavioural Recommendation
only 13% improved among 8 similar
Keep ultra-processed low
GI +5.2 next day on high-intake days · n 26
Keep fat low
GI +4.5 next day on high-intake days · n 20
Keep simple carbs low
GI +3.2 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.4supporter · 95%
Ultra-processed food
+5.2detractor · 95%
Dietary fat load
+4.5detractor · 95%
Simple carbohydrates
+3.2detractor · 87%
Alcohol
-1.4no signal · 31%
Insoluble fibre
+1no signal · 20%
Caffeine
-0.6no signal · 15%
Histamine load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 40/100
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↓45
- WearableResting HR 77 bpm
- WearableShort sleep window
Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.5 h, below personal baseline
Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Intermediate metabolizer
Expected exposure

Microbiome

Shannon diversity 2.8 · butyrate capacity 40/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 65 ms
Sleep: 6.0 h
Steps: 9,293
Resting HR: 76 bpm

Daily log: GI score 24, nutritional resilience 62, adherence 85.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02685	48%	S16	DT-01	improved	47
P-02429	46%	S11	—	—	48
P-02339	45%	S03	DT-01	improved	50
P-02586	45%	S18	DT-01	improved	56
P-02052	44%	S11	HY-01	no change	48
P-02175	44%	S06	—	—	53
P-02588	44%	S05	—	—	46
P-02045	43%	S07	—	—	52
P-02223	43%	S20	HY-01	improved	49
P-02468	43%	S17	—	—	41
P-02573	43%	S10	—	—	52
P-02105	42%	S08	—	—	54