Patient P-02641
Synthetic patientMETA-24 · Day 170 · 25–34 · F · baseline S05Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
33%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S05
- Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 DT-01 recommended — Dosing / Timing Recommendation DT-01
- Day 23 Patient accepted — Started DT-01 in the companion
- Day 28 No meaningful change — Dosing / Timing Recommendation DT-01
What changed?
Trajectory began diverging from predicted response on Day 15.
Primary contributors, last 14 days
- Inflammatory activity+16
- Nutritional resilience-11
- GI instability+10
- Treatment adherence-10
- Toxicity+7
What helped?
- Dosing / Timing Recommendation DT-01Day 22Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable94 min
stable · -2.4 vs previous 14 d
Sleep duration
Wearable5.5 h
improving · +0.3 vs previous 14 d
Energy level
Daily log5.5/10
stable · -0.1 vs previous 14 d
Steps
Wearable9,828
worsening · -389 vs previous 14 d
GI burden
Companion24.3/100
worsening · +1.5 vs previous 14 d
Adherence
Companion85.1 %
worsening · -5.8 vs previous 14 d
Sleep quality
Wearable31.5/100
stable · +1.1 vs previous 14 d
Glucose, CGM daily mean
CGM142 mg/dL
stable · -2.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 59 from the failing basin, 36 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -5.4 next day on high-intake days · n 24
Would not help
- DT-01 Dosing / Timing Recommendationalready tried, no meaningful change
- BR-03 Behavioural Recommendationonly 13% improved among 8 similar
- Keep ultra-processed lowGI +5.2 next day on high-intake days · n 26
- Keep fat lowGI +4.5 next day on high-intake days · n 20
- Keep simple carbs lowGI +3.2 next day on high-intake days · n 17
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.4supporter · 95%
- Ultra-processed food+5.2detractor · 95%
- Dietary fat load+4.5detractor · 95%
- Simple carbohydrates+3.2detractor · 87%
- Alcohol-1.4no signal · 31%
- Insoluble fibre+1no signal · 20%
- Caffeine-0.6no signal · 15%
- Histamine load+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 40/100
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓45
- WearableResting HR 77 bpm
- WearableShort sleep window
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.5 h, below personal baseline
- Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.8 · butyrate capacity 40/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 65 ms
- Sleep
- 6.0 h
- Steps
- 9,293
- Resting HR
- 76 bpm
Daily log: GI score 24, nutritional resilience 62, adherence 85.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02087 | 36% | S01 | BR-03 | no change | 40 |
| P-02437 | 36% | S01 | — | — | 64 |
| P-02522 | 36% | S01 | BR-03 | no change | 40 |
| P-02681 | 36% | S01 | — | — | 51 |
| P-02218 | 35% | S01 | DT-01 | improved | 61 |
| P-02217 | 33% | S01 | — | — | 61 |
| P-02276 | 32% | S01 | — | — | 57 |
| P-02424 | 32% | S01 | — | — | 62 |
| P-02438 | 32% | S01 | — | — | 32 |
| P-02568 | 32% | S01 | — | — | 51 |
| P-02598 | 32% | S01 | — | — | 53 |
| P-02620 | 32% | S01 | HY-01 | improved | 64 |