DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
44/100
vs baseline (day 0)
+3
3 improved · 3 worsened
synthetic signature · consistent with this patient's biology
- 4 opportunists above range: Escherichia coli, Klebsiella pneumoniae, Enterococcus faecium
- 2 keystone species absent
- Shannon 2.76 (expected ≥ 3)
- 4 resistance genes
Pathogens / opportunists4/5
↑ from 3
Keystone species2/8
Diversity1/2
↑ from 0
Metabolic modules0/4
Vitamin synthesis2/7
Oral translocation1/1
Host DNA0/1
Tissue recycling0/1
↓ from 1
Central mechanisms0/2
Virulence factors2/2
Antibiotic resistance genes4/4
↓ from 5
Genetic predisposition2/2
Opportunists above range
Escherichia coli 13.095% AR
Enterococcus faecium 6.548% AR
Klebsiella pneumoniae 3.929% AR
Streptococcus gallolyticus 1.31% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 2.76 · butyrate 725 CPM · SCFA 1137
2 vitamins below
Host & mechanisms
tissue recycling 34/100
oral translocation 3% AR
4 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 13.123 % AR · above range | 13.095 % AR · above range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 3.937 % AR · above range | 3.929 % AR · above range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 0.27 % AR · in range | 6.548 % AR · above range(worsened) | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.05 % AR · in range | 1.31 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 1.312 % AR · above range | 0.057 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.15 % AR · in range | 0.74 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 1.05 % AR · in range | 0.44 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.15 % AR · in range | 1.03 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 1.22 % AR · in range | 0.25 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 1.01 % AR · in range | 0.88 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 1.43 % AR · in range | 0.53 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 3.02 · in range | 2.76 · below range(worsened) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 130 specii · in range | 120 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 702 CPM · in range | 725 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1164 CPM · in range | 1137 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 402 CPM · in range | 404 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 100 CPM · in range | 126 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 280 CPM · below range | 250 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 401 CPM · below range | 400 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 2978 CPM · in range | 2822 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3244 CPM · in range | 3244 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 2673 CPM · in range | 2725 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3515 CPM · in range | 3208 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 4249 CPM · in range | 2890 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 3 % AR · above range | 3 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 161 pb · in range | 163 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 40 /100 · above range | 34 /100 · in range(improved) | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 62 /100 · in range | 58 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 58 /100 · in range | 56 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 31 potriviri/M · present | 85 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 73 potriviri/M · present | 47 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 1.8 citiri/M · present | 4.5 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 4.6 citiri/M · present | 10.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 6.4 citiri/M · present | 2.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 6.5 citiri/M · present | 4.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 8.2 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| FUT2 | 2.96 OR · risk variant | 2.85 OR · risk variant | expected reference genotype | Reduced mucosal fucosylation |
| CYP2D6 | 2.35 OR · risk variant | 2.75 OR · risk variant | expected reference genotype | Expected exposure |