Patient P-01330
Therapy response
Improving
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
64%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 44 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 50 GI-04 recommended — GI Support Protocol GI-04
- Day 51 Patient accepted — Started GI-04 in the companion
- Day 57 ME-01 recommended — Monitoring Escalation ME-01
- Day 58 Patient accepted — Started ME-01 in the companion
- Day 59 GI symptom burden −28% vs expected — GI Support Protocol GI-04
- Day 61 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 65 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 44.
Primary contributors, last 14 days
- Nutritional resilience+9
- GI instability-4
What helped?
- GI Support Protocol GI-04Day 50Result: symptom burden −28%
- Monitoring Escalation ME-01Day 57Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
56%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion47.7/100
stable · +1.7 vs previous 14 d
Toxicity
Blood42.4/100
improving · -10.3 vs previous 14 d
Sleep quality
Wearable37.1/100
improving · +2.5 vs previous 14 d
Energy level
Daily log3.2/10
improving · +0.4 vs previous 14 d
Stress level
Daily log6.5/10
stable · -0.0 vs previous 14 d
Steps
Wearable5,023
stable · +108 vs previous 14 d
Adherence
Companion46.6 %
stable · -0.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 34 from the failing basin, 53 from restoration.
Would help
Would not help
- Keep fat lowGI +4.9 next day on high-intake days · n 26
- Keep histamine lowGI +3.9 next day on high-intake days · n 20
- Keep simple carbs lowGI +3.1 next day on high-intake days · n 24
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.9detractor · 95%
- Histamine load+3.9detractor · 95%
- Simple carbohydrates+3.1detractor · 84%
- Spicy / capsaicin+2.6detractor · 73%
- Alcohol-0.7no signal · 17%
- Insoluble fibre+0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 48 and rising
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 52
- WearableHRV 26 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 24/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓25
- WearableResting HR 75 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 42
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 23 ms
- Sleep
- 6.6 h
- Steps
- 3,568
- Resting HR
- 77 bpm
Daily log: GI score 48, nutritional resilience 50, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 22% | S19 | AD-05 | improved | 61 |
| P-01696 | 30% | S20 | CR-01 | improved | 59 |
| P-01708 | 30% | S07 | CR-01 | improved | 59 |
| P-01371 | 29% | S06 | CR-01 | improved | 63 |
| P-01442 | 29% | S13 | CR-01 | improved | 61 |
| P-01835 | 29% | S17 | CR-01 | improved | 56 |
| P-01388 | 27% | S17 | CR-01 | improved | 59 |
| P-01877 | 27% | S01 | CR-01 | improved | 67 |
| P-01430 | 23% | S05 | CR-01 | improved | 54 |
| P-01767 | 22% | S14 | DT-01 | no change | 63 |
| P-01709 | 63% | S14 | GI-04 | improved | 43 |
| P-01661 | 56% | S03 | GI-04 | improved | 52 |