Patient P-01330
Therapy response
Improving
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
64%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 44 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 50 GI-04 recommended — GI Support Protocol GI-04
- Day 51 Patient accepted — Started GI-04 in the companion
- Day 57 ME-01 recommended — Monitoring Escalation ME-01
- Day 58 Patient accepted — Started ME-01 in the companion
- Day 59 GI symptom burden −28% vs expected — GI Support Protocol GI-04
- Day 61 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 65 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 44.
Primary contributors, last 14 days
- Nutritional resilience+9
- GI instability-4
What helped?
- GI Support Protocol GI-04Day 50Result: symptom burden −28%
- Monitoring Escalation ME-01Day 57Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
56%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 48 and rising
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 52
- WearableHRV 26 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 24/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓25
- WearableResting HR 75 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 42
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 23 ms
- Sleep
- 6.6 h
- Steps
- 3,568
- Resting HR
- 77 bpm
Daily log: GI score 48, nutritional resilience 50, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01709 | 63% | S14 | GI-04 | improved | 43 |
| P-01661 | 56% | S03 | GI-04 | improved | 52 |
| P-01431 | 55% | S14 | GI-04 | improved | 41 |
| P-01518 | 54% | S14 | GI-04 | improved | 40 |
| P-01473 | 53% | S14 | GI-04 | improved | 51 |
| P-01556 | 53% | S14 | GI-04 | improved | 44 |
| P-01879 | 53% | S14 | SC-12 | improved | 51 |
| P-01496 | 52% | S14 | SC-12 | improved | 46 |
| P-01570 | 52% | S14 | SC-12 | improved | 46 |
| P-01573 | 52% | S14 | GI-04 | improved | 49 |
| P-01433 | 51% | S14 | GI-04 | improved | 48 |
| P-01692 | 51% | S14 | NP-02 | improved | 49 |