Patient P-01336
Therapy response
Improving
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
54%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S03
- Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 50 GI-04 recommended — GI Support Protocol GI-04
- Day 51 Patient accepted — Started GI-04 in the companion
- Day 59 GI symptom burden −35% vs expected — GI Support Protocol GI-04
- Day 65 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 45.
Primary contributors, last 14 days
- GI instability-10
- Nutritional resilience+6
- Treatment adherence-2
What helped?
- GI Support Protocol GI-04Day 50Result: symptom burden −35%
LIFE OS recommendation
Dietary Support Protocol NP-02
57%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion50/100
stable · +1.1 vs previous 14 d
Toxicity
Blood40.2/100
stable · -1.6 vs previous 14 d
Sleep quality
Wearable33.2/100
improving · +1.9 vs previous 14 d
Energy level
Daily log3.1/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log6.2/10
stable · -0.2 vs previous 14 d
Steps
Wearable6,819
stable · +178 vs previous 14 d
Adherence
Companion48.4 %
worsening · -3.0 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 35 from the failing basin, 53 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +58.9
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Poor metabolizerhidden · steering -12.7
- Low microbial diversityhidden · steering -7.7
- Dietary fat loadperturbation · steering -7.6
- Dietary fat loaddetractor · GI +3.9 next day
- Simple carbohydratesdetractor · GI +3.9 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.9detractor · 95%
- Simple carbohydrates+3.9detractor · 95%
- Insoluble fibre+2.8detractor · 87%
- Alcohol-2.1no signal · 44%
- Spicy / capsaicin-0.3no signal · 15%
- Histamine load0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 54
- WearableHRV 17 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 32/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 40
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 50 and rising
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.3 · butyrate capacity 32/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 18 ms
- Sleep
- 6.7 h
- Steps
- 6,340
- Resting HR
- 71 bpm
Daily log: GI score 50, nutritional resilience 45, adherence 48.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01661 | 60% | S03 | GI-04 | improved | 52 |
| P-01879 | 55% | S14 | SC-12 | improved | 51 |
| P-01624 | 53% | S14 | GI-04 | improved | 52 |
| P-01400 | 52% | S17 | GI-04 | improved | 51 |
| P-01706 | 52% | S14 | GI-04 | improved | 55 |
| P-01429 | 51% | S09 | GI-04 | improved | 45 |
| P-01393 | 49% | S14 | GI-04 | improved | 53 |
| P-01611 | 49% | S14 | GI-04 | improved | 44 |
| P-01627 | 49% | S14 | GI-04 | improved | 54 |
| P-01462 | 48% | S14 | NP-02 | improved | 47 |
| P-01556 | 48% | S14 | GI-04 | improved | 44 |
| P-01573 | 48% | S14 | GI-04 | improved | 49 |