Patient P-01385

Synthetic patientNBL-101 · Day 114 · 65–74 · M · baseline S06Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S06
Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 HY-01 recommended — Hydration Protocol HY-01
Day 15 Patient accepted — Started HY-01 in the companion
Day 19 GI symptom burden −28% vs expected — Hydration Protocol HY-01
Day 25 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days

GI instability+9
Nutritional resilience-3
Toxicity-3
Treatment adherence-2

What helped?

Hydration Protocol HY-01Day 14
Result: symptom burden −28%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

8.8/100

worsening · +4.3 vs previous 14 d

Toxicity

Blood

10.4/100

worsening · +1.8 vs previous 14 d

Sleep quality

Wearable

58/100

stable · -0.6 vs previous 14 d

Energy level

Daily log

6.4/10

worsening · -0.4 vs previous 14 d

Stress level

Daily log

3.2/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

8,123

stable · +238 vs previous 14 d

Adherence

Companion

98.3 %

stable · +1.5 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 86 from the failing basin, 31 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep fat low
GI +5.8 next day on high-intake days · n 18
Keep alcohol low
GI +5.5 next day on high-intake days · n 19
Keep simple carbs low
GI +4.1 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+5.8detractor · 95%
Alcohol
+5.5detractor · 95%
Simple carbohydrates
+4.1detractor · 95%
Spicy / capsaicin
+0.8no signal · 15%
Insoluble fibre
+0.6no signal · 15%
Histamine load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.4 · butyrate capacity 44/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 59 ms
Sleep: 6.8 h
Steps: 8,888
Resting HR: 68 bpm

Daily log: GI score 9, nutritional resilience 71, adherence 98.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01541	38%	S09	AD-05	no change	43
P-01377	37%	S11	AD-05	no change	42
P-01483	37%	S14	AD-05	no change	35
P-01679	31%	S12	AD-05	no change	39
P-01804	29%	S19	AD-05	improved	61
P-01773	28%	S05	AD-05	improved	27
P-01848	28%	S05	AD-05	no change	23
P-01313	37%	S01	BR-03	improved	32
P-01468	35%	S06	BR-03	no change	41
P-01450	34%	S09	BR-03	no change	36
P-01689	33%	S13	BR-03	no change	50
P-01350	32%	S19	BR-03	no change	34