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Patient P-01385

Synthetic patientNBL-101 · Day 114 · 65–74 · M · baseline S06Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S06
  2. Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 14 HY-01 recommended — Hydration Protocol HY-01
  4. Day 15 Patient accepted — Started HY-01 in the companion
  5. Day 19 GI symptom burden −28% vs expected — Hydration Protocol HY-01
  6. Day 25 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days
  • GI instability+9
  • Nutritional resilience-3
  • Toxicity-3
  • Treatment adherence-2

What helped?

  • Hydration Protocol HY-01Day 14
    Result: symptom burden −28%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
8.8/100
worsening · +4.3 vs previous 14 d
Toxicity
Blood
10.4/100
worsening · +1.8 vs previous 14 d
Sleep quality
Wearable
58/100
stable · -0.6 vs previous 14 d
Energy level
Daily log
6.4/10
worsening · -0.4 vs previous 14 d
Stress level
Daily log
3.2/10
worsening · +0.3 vs previous 14 d
Steps
Wearable
8,123
stable · +238 vs previous 14 d
Adherence
Companion
98.3 %
stable · +1.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 86 from the failing basin, 31 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
Would not help
  • Keep fat low
    GI +5.8 next day on high-intake days · n 18
  • Keep alcohol low
    GI +5.5 next day on high-intake days · n 19
  • Keep simple carbs low
    GI +4.1 next day on high-intake days · n 18
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +5.8detractor · 95%
  • Alcohol
    +5.5detractor · 95%
  • Simple carbohydrates
    +4.1detractor · 95%
  • Spicy / capsaicin
    +0.8no signal · 15%
  • Insoluble fibre
    +0.6no signal · 15%
  • Histamine load
    +0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production ↓60
    • MicrobiomeButyrate capacity 44/100
    • MicrobiomeF. prausnitzii depleted
  • Drug metabolism and exposure ↑35
    • DNADPYD *2A → slower clearance
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
  • DPYD *2A heterozygous
    Slower drug clearance
  • CYP2D6 Rapid metabolizer
    Expected exposure
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 2.4 · butyrate capacity 44/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
59 ms
Sleep
6.8 h
Steps
8,888
Resting HR
68 bpm
Daily log: GI score 9, nutritional resilience 71, adherence 98.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0155554%S06GI-04improved56
P-0166649%S03——55
P-0161848%S10GI-04improved39
P-0159646%S08——51
P-0137445%S08HY-01improved49
P-0163345%S16GI-04no change55
P-0152244%S06DT-01no change62
P-0132043%S09HY-01improved38
P-0189443%S19HY-01no change45
P-0148742%S03——48
P-0151342%S19GI-04no change53
P-0186142%S12HY-01improved47