Patient P-01430

Synthetic patientNBL-101 · Day 95 · 45–54 · F · baseline S05Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S05
Day 23 CR-01 recommended — Clinician Review CR-01
Day 24 Patient accepted — Started CR-01 in the companion
Day 29 Deterioration detected before clinical escalation — Clinician Review CR-01

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

GI instability-12
Nutritional resilience+8
Treatment adherence-5
Toxicity+5

What helped?

Clinician Review CR-01Day 23
Result: deterioration detected before clinical escalation

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

20.6/100

worsening · +4.1 vs previous 14 d

Toxicity

Blood

21.9/100

stable · -0.5 vs previous 14 d

Sleep quality

Wearable

25.7/100

stable · +0.6 vs previous 14 d

Energy level

Daily log

5.9/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

5.3/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

7,611

stable · +45 vs previous 14 d

Adherence

Companion

89.6 %

stable · -0.4 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 67 from the failing basin, 26 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep spicy low
GI +4.6 next day on high-intake days · n 16

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Spicy / capsaicin
+4.6detractor · 95%
Alcohol
+1.4no signal · 26%
Insoluble fibre
+1.2no signal · 26%
Dietary fat load
+0.5no signal · 15%
Histamine load
+0.4no signal · 15%
Simple carbohydrates
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↑45
- WearableResting HR 76 bpm
- WearableShort sleep window
Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.1 h, below personal baseline
Inflammatory signalling ↓40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 36 ms, trending down
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 4.1 · butyrate capacity 82/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 36 ms
Sleep: 6.2 h
Steps: 7,521
Resting HR: 78 bpm

Daily log: GI score 21, nutritional resilience 66, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01804	45%	S19	AD-05	improved	61
P-01377	35%	S11	AD-05	no change	42
P-01541	35%	S09	AD-05	no change	43
P-01483	33%	S14	AD-05	no change	35
P-01679	31%	S12	AD-05	no change	39
P-01773	28%	S05	AD-05	improved	27
P-01313	32%	S01	BR-03	improved	32
P-01350	32%	S19	BR-03	no change	34
P-01689	32%	S13	BR-03	no change	50
P-01468	30%	S06	BR-03	no change	41
P-01450	28%	S09	BR-03	no change	36
P-01371	27%	S06	CR-01	improved	63