Patient P-01432

Synthetic patientNBL-101 · Day 112 · 55–64 · F · baseline S14Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Stable

Discontinuation risk

49%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S14
Day 44 SC-12 recommended — Supportive Compound SC-12
Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 45 Patient accepted — Started SC-12 in the companion
Day 51 GI symptom burden −24% vs expected — Supportive Compound SC-12
Day 52 GI-04 recommended — GI Support Protocol GI-04
Day 53 Patient accepted — Started GI-04 in the companion
Day 57 Tolerance state changed — Unstable → Improving
Day 61 GI symptom burden −39% vs expected — GI Support Protocol GI-04
Day 67 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 45.

Primary contributors, last 14 days

Treatment adherence+8
Inflammatory activity-2
Toxicity+2

What helped?

Supportive Compound SC-12Day 44
Result: symptom burden −24%
GI Support Protocol GI-04Day 52
Result: symptom burden −39%

LIFE OS recommendation

Adherence Support AD-05

30%

probability of meaningful tolerance improvement

284 similar trajectories
20% showed improvement
median effect visible after 5 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

32.5/100

improving · -4.0 vs previous 14 d

Toxicity

Blood

32.7/100

worsening · +2.5 vs previous 14 d

Sleep quality

Wearable

56.6/100

stable · -0.0 vs previous 14 d

Energy level

Daily log

5/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

3.9/10

improving · -0.4 vs previous 14 d

Steps

Wearable

7,796

stable · -153 vs previous 14 d

Adherence

Companion

57 %

stable · +0.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 54 from the failing basin, 37 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep simple carbs low
GI +6.6 next day on high-intake days · n 20
Keep fat low
GI +6.2 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
+6.6detractor · 95%
Dietary fat load
+6.2detractor · 95%
Histamine load
-1.7no signal · 30%
Insoluble fibre
-0.9no signal · 16%
Alcohol
+0.9no signal · 15%
Spicy / capsaicin
-0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 35/100
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.4 · butyrate capacity 35/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 55 ms
Sleep: 7.7 h
Steps: 9,064
Resting HR: 70 bpm

Daily log: GI score 33, nutritional resilience 59, adherence 57.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01405	61%	S14	SC-12	improved	44
P-01383	52%	S14	NP-02	improved	40
P-01678	52%	S14	GI-04	improved	44
P-01588	45%	S14	GI-04	improved	57
P-01568	44%	S14	GI-04	improved	40
P-01458	42%	S14	GI-04	improved	44
P-01617	42%	S14	SC-12	improved	50
P-01632	42%	S14	GI-04	improved	36
P-01686	42%	S10	GI-04	improved	43
P-01714	42%	S14	GI-04	improved	66
P-01574	41%	S14	GI-04	improved	47
P-01649	41%	S14	GI-04	improved	46