Patient P-01581
Synthetic patientNBL-101 · Day 120 · 55–64 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Stable
GI state
Deteriorating
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
70%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S18
- Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 59 GI-04 recommended — GI Support Protocol GI-04
- Day 60 Patient accepted — Started GI-04 in the companion
- Day 68 GI symptom burden −20% vs expected — GI Support Protocol GI-04
- Day 70 ME-01 recommended — Monitoring Escalation ME-01
- Day 71 Patient accepted — Started ME-01 in the companion
- Day 74 Tolerance state changed — Unstable → Improving
- Day 74 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 50.
Primary contributors, last 14 days
- Inflammatory activity+14
- Nutritional resilience-11
- GI instability+10
- Treatment adherence+6
What helped?
- GI Support Protocol GI-04Day 59Result: symptom burden −20%
- Monitoring Escalation ME-01Day 70Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
57%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion52.8/100
stable · -1.0 vs previous 14 d
Toxicity
Blood49.5/100
stable · +1.5 vs previous 14 d
Sleep quality
Wearable43.2/100
worsening · -1.9 vs previous 14 d
Energy level
Daily log2.6/10
improving · +0.1 vs previous 14 d
Stress level
Daily log6/10
stable · +0.2 vs previous 14 d
Steps
Wearable3,053
improving · +389 vs previous 14 d
Adherence
Companion52.3 %
stable · +0.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 31 from the failing basin, 58 from restoration.
Would help
Would not help
- Keep fat lowGI +6.2 next day on high-intake days · n 21
- Keep spicy lowGI +4.5 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.2detractor · 95%
- Spicy / capsaicin+4.5detractor · 95%
- Insoluble fibre+1.9no signal · 33%
- Alcohol+1.2no signal · 21%
- Histamine load+0.2no signal · 15%
- Simple carbohydrates+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 31/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 60
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- Autonomic recovery ↓45
- WearableResting HR 75 bpm
- Wearable3,053 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 50
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 3.2 · butyrate capacity 31/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 55 ms
- Sleep
- 6.6 h
- Steps
- 2,172
- Resting HR
- 75 bpm
Daily log: GI score 53, nutritional resilience 41, adherence 52.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01831 | 59% | S15 | SC-12 | improved | 49 |
| P-01436 | 50% | S14 | GI-04 | improved | 38 |
| P-01842 | 50% | S14 | NP-02 | improved | 55 |
| P-01389 | 49% | S14 | SC-12 | improved | 46 |
| P-01544 | 49% | S15 | GI-04 | improved | 50 |
| P-01781 | 49% | S14 | NP-02 | improved | 45 |
| P-01486 | 48% | S18 | GI-04 | improved | 47 |
| P-01307 | 47% | S14 | GI-04 | improved | 43 |
| P-01412 | 47% | S14 | NP-02 | improved | 49 |
| P-01356 | 46% | S14 | GI-04 | improved | 42 |
| P-01365 | 46% | S14 | SC-12 | improved | 49 |
| P-01413 | 46% | S14 | GI-04 | improved | 44 |