Patient P-01632
Therapy response
Unstable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Stable
Nutritional resilience
Declining
Discontinuation risk
56%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 48 SC-12 recommended — Supportive Compound SC-12
- Day 49 Patient accepted — Started SC-12 in the companion
- Day 55 GI symptom burden −12% vs expected — Supportive Compound SC-12
- Day 58 GI-04 recommended — GI Support Protocol GI-04
- Day 58 ME-01 recommended — Monitoring Escalation ME-01
- Day 59 Patient accepted — Started GI-04 in the companion
- Day 59 Patient accepted — Started ME-01 in the companion
- Day 61 Tolerance state changed — Unstable → Improving
- Day 62 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 67 GI symptom burden −27% vs expected — GI Support Protocol GI-04
- Day 73 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- Nutritional resilience-8
- GI instability+3
- Treatment adherence+3
- Toxicity-3
What helped?
- Supportive Compound SC-12Day 48Result: symptom burden −12%
- GI Support Protocol GI-04Day 58Result: symptom burden −27%
- Monitoring Escalation ME-01Day 58Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
59%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 75% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion35/100
improving · -4.4 vs previous 14 d
Toxicity
Blood39/100
stable · -1.0 vs previous 14 d
Sleep quality
Wearable40.4/100
stable · -0.2 vs previous 14 d
Energy level
Daily log3.6/10
stable · -0.1 vs previous 14 d
Stress level
Daily log4.4/10
stable · -0.1 vs previous 14 d
Steps
Wearable7,382
stable · -28 vs previous 14 d
Adherence
Companion54.4 %
improving · +3.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 43 from the failing basin, 50 from restoration.
Would help
Would not help
- Keep fat lowGI +4.1 next day on high-intake days · n 20
- Keep histamine lowGI +3.5 next day on high-intake days · n 18
- Keep simple carbs lowGI +2.8 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.1detractor · 95%
- Histamine load+3.5detractor · 95%
- Simple carbohydrates+2.8detractor · 95%
- Spicy / capsaicin+1.8detractor · 58%
- Alcohol-0.9no signal · 26%
- Insoluble fibre-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↑50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 42
- Autonomic recovery ↑45
- WearableResting HR 80 bpm
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.1 · butyrate capacity 29/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 59 ms
- Sleep
- 6.9 h
- Steps
- 6,404
- Resting HR
- 80 bpm
Daily log: GI score 35, nutritional resilience 45, adherence 54.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01678 | 50% | S14 | GI-04 | improved | 44 |
| P-01356 | 48% | S14 | GI-04 | improved | 42 |
| P-01405 | 46% | S14 | SC-12 | improved | 44 |
| P-01383 | 44% | S14 | NP-02 | improved | 40 |
| P-01458 | 44% | S14 | GI-04 | improved | 44 |
| P-01568 | 44% | S14 | GI-04 | improved | 40 |
| P-01617 | 44% | S14 | SC-12 | improved | 50 |
| P-01713 | 44% | S04 | GI-04 | improved | 46 |
| P-01307 | 43% | S14 | GI-04 | improved | 43 |
| P-01746 | 43% | S14 | NP-02 | improved | 47 |
| P-01432 | 42% | S14 | GI-04 | improved | 46 |
| P-01559 | 42% | S06 | GI-04 | improved | 42 |