600 patients66,869 observations120 daysLIVE
← Patients

Patient P-01656

Synthetic patientNBL-101 · Day 103 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
83%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S14
  2. Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 53 GI-04 recommended — GI Support Protocol GI-04
  4. Day 54 Patient accepted — Started GI-04 in the companion
  5. Day 62 No meaningful change — GI Support Protocol GI-04
  6. Day 68 ME-01 recommended — Monitoring Escalation ME-01
  7. Day 69 Patient accepted — Started ME-01 in the companion
  8. Day 72 Deterioration detected before clinical escalation — Monitoring Escalation ME-01

What changed?

Trajectory began diverging from predicted response on Day 48.

Primary contributors, last 14 days
  • GI instability+7
  • Inflammatory activity+6
  • Nutritional resilience+2
  • Treatment adherence+2

What helped?

  • GI Support Protocol GI-04Day 53
    Result: no meaningful change
  • Monitoring Escalation ME-01Day 68
    Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
61%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 66% showed improvement
  • median effect visible after 10 days
View similar patientsSimulateAdd to intervention cohortAll evidence

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
65.8/100
improving · -2.9 vs previous 14 d
Toxicity
Blood
46.9/100
stable · +1.0 vs previous 14 d
Sleep quality
Wearable
33.9/100
worsening · -1.9 vs previous 14 d
Energy level
Daily log
3.3/10
improving · +0.2 vs previous 14 d
Stress level
Daily log
6.8/10
stable · +0.1 vs previous 14 d
Steps
Wearable
3,456
stable · +147 vs previous 14 d
Adherence
Companion
48.4 %
stable · -1.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 19 from the failing basin, 72 from restoration.

Would help
  • NP-02 Dietary Support Protocol
    63% improved among 64 similar · onset 10 d · confidence 75%
  • SC-12 Supportive Compound
    76% improved among 51 similar · onset 6 d · confidence 75%
  • CR-01 Clinician Review
    100% improved among 8 similar · onset 5 d · confidence 75%
Would not help
  • GI-04 GI Support Protocol
    already tried, no meaningful change
  • Keep fat low
    GI +4 next day on high-intake days · n 24
  • Keep histamine low
    GI +3.8 next day on high-intake days · n 23
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +4detractor · 95%
  • Histamine load
    +3.8detractor · 95%
  • Alcohol
    -1.2no signal · 26%
  • Spicy / capsaicin
    +0.7no signal · 18%
  • Simple carbohydrates
    +0.6no signal · 15%
  • Insoluble fibre
    0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Inflammatory signalling ↑60
    • MicrobiomeBacteroides fragilis expansion
    • BloodInflammatory load index 62
    • WearableHRV 36 ms, trending down
  • Butyrate / short-chain fatty acid production ↓55
    • MicrobiomeButyrate capacity 29/100
    • Daily logFibre intake low in recent food logs
  • Mucosal barrier integrity ↓50
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Daily logGI symptom score 66 and rising
  • Drug metabolism and exposure ↑20
    • BloodToxicity index 47
  • Autonomic recovery ↓20
    • Wearable3,456 steps/day
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 29/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
37 ms
Sleep
6.9 h
Steps
4,136
Resting HR
71 bpm
Daily log: GI score 66, nutritional resilience 39, adherence 48.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0183458%S14NP-02improved44
P-0156455%S14ME-01improved39
P-0172855%S14SC-12improved41
P-0173254%S14ME-01improved45
P-0187252%S14NP-02improved47
P-0140951%S14SC-12improved41
P-0141251%S14NP-02improved49
P-0160551%S14ME-01improved41
P-0175151%S14ME-01improved48
P-0189751%S14ME-01improved43
P-0172049%S14NP-02improved47
P-0181049%S05NP-02improved43