Patient P-01707
Synthetic patientNBL-101 · Day 112 · 35–44 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
60%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 44 SC-12 recommended — Supportive Compound SC-12
- Day 45 Patient accepted — Started SC-12 in the companion
- Day 49 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 51 GI symptom burden −13% vs expected — Supportive Compound SC-12
- Day 52 GI-04 recommended — GI Support Protocol GI-04
- Day 53 Patient accepted — Started GI-04 in the companion
- Day 57 Tolerance state changed — Unstable → Improving
- Day 61 GI symptom burden −26% vs expected — GI Support Protocol GI-04
- Day 67 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 49.
Primary contributors, last 14 days
- GI instability-12
- Toxicity-9
- Inflammatory activity-8
- Nutritional resilience+3
What helped?
- Supportive Compound SC-12Day 44Result: symptom burden −13%
- GI Support Protocol GI-04Day 52Result: symptom burden −26%
LIFE OS recommendation
Dietary Support Protocol NP-02
55%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion43.9/100
improving · -4.8 vs previous 14 d
Toxicity
Blood42.5/100
stable · +0.4 vs previous 14 d
Sleep quality
Wearable29.9/100
improving · +5.5 vs previous 14 d
Energy level
Daily log3.9/10
improving · +0.5 vs previous 14 d
Stress level
Daily log5.9/10
improving · -0.3 vs previous 14 d
Steps
Wearable2,322
worsening · -590 vs previous 14 d
Adherence
Companion52.4 %
stable · +0.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 46 from the failing basin, 42 from restoration.
Would help
Would not help
- Keep fat lowGI +4.2 next day on high-intake days · n 18
- Keep simple carbs lowGI +3.7 next day on high-intake days · n 19
- Keep spicy lowGI +1.9 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.2detractor · 95%
- Simple carbohydrates+3.7detractor · 95%
- Spicy / capsaicin+1.9detractor · 64%
- Histamine load+1.2no signal · 33%
- Insoluble fibre+0.9no signal · 19%
- Alcohol-0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 37/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.4 h, below personal baseline
- Autonomic recovery ↑40
- Wearable2,322 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.7 · butyrate capacity 37/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 53 ms
- Sleep
- 5.4 h
- Steps
- 2,694
- Resting HR
- 69 bpm
Daily log: GI score 44, nutritional resilience 43, adherence 52.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01327 | 41% | S01 | GI-04 | improved | 56 |
| P-01688 | 33% | S01 | GI-04 | improved | 40 |
| P-01813 | 30% | S01 | NP-02 | no change | 40 |
| P-01310 | 29% | S01 | — | — | 57 |
| P-01821 | 24% | S01 | — | — | 58 |
| P-01877 | 24% | S01 | CR-01 | improved | 67 |
| P-01604 | 23% | S01 | — | — | 71 |
| P-01823 | 23% | S01 | — | — | 57 |
| P-01635 | 38% | S02 | GI-04 | improved | 49 |
| P-01452 | 32% | S02 | GI-04 | improved | 46 |
| P-01459 | 27% | S02 | — | — | 51 |
| P-01498 | 24% | S02 | — | — | 56 |