600 patients66,869 observations120 daysLIVE

Patient P-01707

Synthetic patientNBL-101 · Day 112 · 35–44 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
60%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S14
  2. Day 44 SC-12 recommendedSupportive Compound SC-12
  3. Day 45 Patient acceptedStarted SC-12 in the companion
  4. Day 49 Trajectory diverged from predictionObserved response fell below the model's expected path.
  5. Day 51 GI symptom burden −13% vs expectedSupportive Compound SC-12
  6. Day 52 GI-04 recommendedGI Support Protocol GI-04
  7. Day 53 Patient acceptedStarted GI-04 in the companion
  8. Day 57 Tolerance state changedUnstable → Improving
  9. Day 61 GI symptom burden −26% vs expectedGI Support Protocol GI-04
  10. Day 67 Tolerance state changedUnstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 49.

Primary contributors, last 14 days
  • GI instability-12
  • Toxicity-9
  • Inflammatory activity-8
  • Nutritional resilience+3

What helped?

  • Supportive Compound SC-12Day 44
    Result: symptom burden −13%
  • GI Support Protocol GI-04Day 52
    Result: symptom burden −26%
LIFE OS recommendation
Dietary Support Protocol NP-02
55%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 66% showed improvement
  • median effect visible after 10 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
43.9/100
improving · -4.8 vs previous 14 d
Toxicity
Blood
42.5/100
stable · +0.4 vs previous 14 d
Sleep quality
Wearable
29.9/100
improving · +5.5 vs previous 14 d
Energy level
Daily log
3.9/10
improving · +0.5 vs previous 14 d
Stress level
Daily log
5.9/10
improving · -0.3 vs previous 14 d
Steps
Wearable
2,322
worsening · -590 vs previous 14 d
Adherence
Companion
52.4 %
stable · +0.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 46 from the failing basin, 42 from restoration.

Would help
  • ME-01 Monitoring Escalation
    100% improved among 77 similar · onset 3 d · confidence 66%
  • NP-02 Dietary Support Protocol
    63% improved among 64 similar · onset 10 d · confidence 66%
  • CR-01 Clinician Review
    100% improved among 8 similar · onset 5 d · confidence 66%
Would not help
  • Keep fat low
    GI +4.2 next day on high-intake days · n 18
  • Keep simple carbs low
    GI +3.7 next day on high-intake days · n 19
  • Keep spicy low
    GI +1.9 next day on high-intake days · n 19
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +4.2detractor · 95%
  • Simple carbohydrates
    +3.7detractor · 95%
  • Spicy / capsaicin
    +1.9detractor · 64%
  • Histamine load
    +1.2no signal · 33%
  • Insoluble fibre
    +0.9no signal · 19%
  • Alcohol
    -0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production 80
    • MicrobiomeButyrate capacity 37/100
    • MicrobiomeF. prausnitzii depleted
    • Daily logFibre intake low in recent food logs
  • Inflammatory signalling 70
    • DNAIL6 -174 variant raises baseline inflammatory tone
    • MicrobiomeBacteroides fragilis expansion
    • BloodInflammatory load index 48
  • Mucosal barrier integrity 40
    • MicrobiomeAkkermansia low → thinner mucus layer
    • WearableSleep 5.4 h, below personal baseline
  • Autonomic recovery 40
    • Wearable2,322 steps/day
    • WearableShort sleep window
  • Drug metabolism and exposure 20
    • BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
  • IL6 -174 G/C
    Higher inflammatory tone
  • CYP2D6 Normal metabolizer
    Expected exposure
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 2.7 · butyrate capacity 37/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
53 ms
Sleep
5.4 h
Steps
2,694
Resting HR
69 bpm
Daily log: GI score 44, nutritional resilience 43, adherence 52.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0137723%S11AD-05no change42
P-0168923%S13BR-03no change50
P-0170830%S07CR-01improved59
P-0137129%S06CR-01improved63
P-0169627%S20CR-01improved59
P-0138825%S17CR-01improved59
P-0144225%S13CR-01improved61
P-0143024%S05CR-01improved54
P-0183524%S17CR-01improved56
P-0187724%S01CR-01improved67
P-0176723%S14DT-01no change63
P-0147350%S14GI-04improved51