Patient P-01755

Synthetic patientNBL-101 · Day 120 · 55–64 · M · baseline S13Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

24%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S13
Day 31 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 31.

Primary contributors, last 14 days

Treatment adherence-7
Toxicity-6
GI instability+3
Inflammatory activity+3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

29/100

improving · -10.3 vs previous 14 d

Toxicity

Blood

21/100

worsening · +2.1 vs previous 14 d

Sleep quality

Wearable

53/100

improving · +11.7 vs previous 14 d

Energy level

Daily log

4.9/10

improving · +0.5 vs previous 14 d

Stress level

Daily log

3.2/10

improving · -0.4 vs previous 14 d

Steps

Wearable

3,319

improving · +571 vs previous 14 d

Adherence

Companion

91.5 %

stable · +1.7 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 63 from the failing basin, 24 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Enterobacteriaceae elevated
hidden · steering -7.4
Poor-sleep week
perturbation · steering -3

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
-3.1no signal · 53%
Dietary fat load
-2.7no signal · 50%
Insoluble fibre
-1.4no signal · 25%
Simple carbohydrates
-1.1no signal · 20%
Spicy / capsaicin
+0.8no signal · 15%
Alcohol
+0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↑45
- WearableResting HR 76 bpm
- Wearable3,319 steps/day
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.9 · butyrate capacity 71/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 62 ms
Sleep: 6.6 h
Steps: 4,109
Resting HR: 75 bpm

Daily log: GI score 29, nutritional resilience 63, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01377	36%	S11	AD-05	no change	42
P-01804	34%	S19	AD-05	improved	61
P-01541	33%	S09	AD-05	no change	43
P-01483	32%	S14	AD-05	no change	35
P-01679	30%	S12	AD-05	no change	39
P-01689	35%	S13	BR-03	no change	50
P-01468	31%	S06	BR-03	no change	41
P-01313	29%	S01	BR-03	improved	32
P-01350	29%	S19	BR-03	no change	34
P-01450	29%	S09	BR-03	no change	36
P-01329	27%	S08	BR-03	improved	79
P-01677	27%	S05	BR-03	no change	86