600 patients66,869 observations120 daysLIVE

Patient P-01755

Synthetic patientNBL-101 · Day 120 · 55–64 · M · baseline S13Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
24%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S13
  2. Day 31 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 31.

Primary contributors, last 14 days
  • Treatment adherence-7
  • Toxicity-6
  • GI instability+3
  • Inflammatory activity+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    29/100
    improving · -10.3 vs previous 14 d
    Toxicity
    Blood
    21/100
    worsening · +2.1 vs previous 14 d
    Sleep quality
    Wearable
    53/100
    improving · +11.7 vs previous 14 d
    Energy level
    Daily log
    4.9/10
    improving · +0.5 vs previous 14 d
    Stress level
    Daily log
    3.2/10
    improving · -0.4 vs previous 14 d
    Steps
    Wearable
    3,319
    improving · +571 vs previous 14 d
    Adherence
    Companion
    91.5 %
    stable · +1.7 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 63 from the failing basin, 24 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • Enterobacteriaceae elevated
      hidden · steering -7.4
    • Poor-sleep week
      perturbation · steering -3
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      -3.1no signal · 53%
    • Dietary fat load
      -2.7no signal · 50%
    • Insoluble fibre
      -1.4no signal · 25%
    • Simple carbohydrates
      -1.1no signal · 20%
    • Spicy / capsaicin
      +0.8no signal · 15%
    • Alcohol
      +0.5no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery 45
      • WearableResting HR 76 bpm
      • Wearable3,319 steps/day
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity 30
      • MicrobiomeAkkermansia low → thinner mucus layer
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.9 · butyrate capacity 71/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    62 ms
    Sleep
    6.6 h
    Steps
    4,109
    Resting HR
    75 bpm
    Daily log: GI score 29, nutritional resilience 63, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0160439%S0171
    P-0170339%S0151
    P-0145538%S01GI-04improved61
    P-0182138%S0158
    P-0182336%S0157
    P-0173131%S01ME-01improved32
    P-0184630%S0137
    P-0131329%S01BR-03improved32
    P-0184729%S0137
    P-0140828%S0177
    P-0181628%S0135
    P-0169527%S0130