Patient P-01760
Synthetic patientNBL-101 · Day 111 · 45–54 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 50.
Primary contributors, last 14 days
- Treatment adherence+5
- Inflammatory activity+4
- GI instability+3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion65.1/100
worsening · +4.9 vs previous 14 d
Toxicity
Blood52.8/100
improving · -2.4 vs previous 14 d
Sleep quality
Wearable19.2/100
worsening · -0.8 vs previous 14 d
Energy level
Daily log2.4/10
worsening · -0.1 vs previous 14 d
Stress level
Daily log7/10
stable · -0.0 vs previous 14 d
Steps
Wearable300
worsening · -152 vs previous 14 d
Adherence
Companion42.5 %
worsening · -2.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 18 from the failing basin, 74 from restoration.
Would help
Would not help
- Keep histamine lowGI +3.6 next day on high-intake days · n 20
- Keep alcohol lowGI +3.6 next day on high-intake days · n 18
- Keep fat lowGI +3.5 next day on high-intake days · n 25
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+3.6detractor · 95%
- Alcohol+3.6detractor · 95%
- Dietary fat load+3.5detractor · 95%
- Simple carbohydrates+3.1detractor · 95%
- Spicy / capsaicin+2.4detractor · 84%
- Insoluble fibre-0.8no signal · 22%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 65 and rising
- WearableSleep 5.9 h, below personal baseline
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 65
- WearableHRV 21 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 42/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑65
- WearableResting HR 85 bpm
- Wearable300 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 53
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 1.9 · butyrate capacity 42/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 16 ms
- Sleep
- 6.0 h
- Steps
- 582
- Resting HR
- 88 bpm
Daily log: GI score 65, nutritional resilience 37, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01454 | 57% | S14 | GI-04 | no change | 49 |
| P-01605 | 57% | S14 | ME-01 | improved | 41 |
| P-01655 | 54% | S14 | GI-04 | no change | 29 |
| P-01407 | 53% | S14 | NP-02 | no change | 44 |
| P-01751 | 53% | S14 | ME-01 | improved | 48 |
| P-01822 | 53% | S14 | — | — | 37 |
| P-01656 | 52% | S14 | ME-01 | improved | 41 |
| P-01813 | 52% | S01 | NP-02 | no change | 40 |
| P-01865 | 52% | S14 | NP-02 | no change | 51 |
| P-01866 | 52% | S14 | — | — | 40 |
| P-01732 | 51% | S14 | ME-01 | improved | 45 |
| P-01872 | 51% | S14 | NP-02 | improved | 47 |