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Patient P-01823

Synthetic patientNBL-101 · Day 114 · 35–44 · F · baseline S01Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S01
  2. Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days
  • Inflammatory activity+8
  • Treatment adherence-7
  • Nutritional resilience-6
  • GI instability+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    29.2/100
    improving · -9.9 vs previous 14 d
    Toxicity
    Blood
    13.1/100
    improving · -3.5 vs previous 14 d
    Sleep quality
    Wearable
    26.1/100
    improving · +3.2 vs previous 14 d
    Energy level
    Daily log
    5.8/10
    improving · +0.9 vs previous 14 d
    Stress level
    Daily log
    5.5/10
    improving · -0.6 vs previous 14 d
    Steps
    Wearable
    1,664
    improving · +376 vs previous 14 d
    Adherence
    Companion
    88.9 %
    stable · +0.6 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 62 from the failing basin, 26 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep fat low
      GI +5.8 next day on high-intake days · n 17
    • Keep alcohol low
      GI +4.7 next day on high-intake days · n 21
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Dietary fat load
      +5.8detractor · 95%
    • Alcohol
      +4.7detractor · 95%
    • Histamine load
      -1.6no signal · 30%
    • Spicy / capsaicin
      -1.4no signal · 18%
    • Simple carbohydrates
      +0.6no signal · 15%
    • Insoluble fibre
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑75
      • DNACYP2D6 poor metabolizer → higher exposure
      • DNADPYD *2A → slower clearance
    • Autonomic recovery ↑65
      • WearableResting HR 74 bpm
      • Wearable1,664 steps/day
      • WearableShort sleep window
    • Mucosal barrier integrity ↓40
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.8 h, below personal baseline
    • Butyrate / short-chain fatty acid production ↓35
      • MicrobiomeButyrate capacity 22/100
    • Inflammatory signalling ↑15
      • WearableHRV 34 ms, trending down
    DNA
    Fictional pharmacogenomic panel
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.1 · butyrate capacity 22/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    33 ms
    Sleep
    6.0 h
    Steps
    2,941
    Resting HR
    73 bpm
    Daily log: GI score 29, nutritional resilience 52, adherence 89.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0180438%S19AD-05improved61
    P-0154133%S09AD-05no change43
    P-0137732%S11AD-05no change42
    P-0148331%S14AD-05no change35
    P-0167930%S12AD-05no change39
    P-0168931%S13BR-03no change50
    P-0131330%S01BR-03improved32
    P-0135030%S19BR-03no change34
    P-0146829%S06BR-03no change41
    P-0145028%S09BR-03no change36
    P-0143040%S05CR-01improved54
    P-0137129%S06CR-01improved63